Protein Alignment CG12766 and AKR7L

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_001335350.1
• Gene: AKR7L / 246181
• HGNCID: 24056
• Length: 331
• Species: Homo sapiens
• Alignment Length: 208
• Identity: 51/208 - (24%)
• Similarity: 79/208 - (37%)
• Gaps: 63/208 - (30%)

  Fly    26 ASTEGDCERAVLHAIDVGYRHIDTAYFYGN-EAEV---GAAVRKKIAEGVIKREDIFITTKL--W 84
            |.|.....||.|   :.|:..||||:.|.: ::|.   |..:|...::..:|     |.||.  |
Human    25 APTSAAVTRAFL---ERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVK-----IATKANPW 81

  Fly    85 C-NFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEVELVDIDYLDTW 148
            . |..:|:.|......:||.:....|||:.:|.|              |.:..||       :|.
Human    82 IGNSLKPDSVRSQLETSLKRLQCPRVDLFYLHAP--------------DHSAPVE-------ETL 125

  Fly   149 GAMEKLVDLGLTKSIGVSNFNEEQLTRLLANCKIKPIHNQIEVHPALDQKKLIALCKKNG-ILVT 212
            .|..:|...|....:|:||:                        .|.:..::..|||.|| ||.|
Human   126 RACHQLHQEGKFVELGLSNY------------------------AAWEVAEICTLCKSNGWILPT 166

  Fly   213 AFSPLGRHNAELR 225
            .:.  |.::|..|
Human   167 VYQ--GMYSATTR 177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	51/208 (25%)
AKR7L	NP_001335350.1	AKR_AKR7A1-5	10..319	CDD:381301	51/208 (25%)