Protein Alignment CG12766 and AKR1B1

DIOPT Version :9

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_001619.1
• Gene: AKR1B1 / 231
• HGNCID: 381
• Length: 316
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 150/308 - (48%)
• Similarity: 201/308 - (65%)
• Gaps: 7/308 - (2%)

  Fly    12 NDGTHIQGIGLGTFASTEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVIKRED 76
            |:|..:..:||||:.|..|....||..||||||||||.|:.|.||.|||.|:::|:.|.|:|||:
Human     8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREE 72

  Fly    77 IFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEVELVD 141
            :||.:||||.:||...|:.||:|||.::.|||:||||||||..:|  ...|..|.|.:|.|...|
Human    73 LFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK--PGKEFFPLDESGNVVPSD 135

  Fly   142 IDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLL--ANCKIKPIHNQIEVHPALDQKKLIALC 204
            .:.||||.|||:|||.||.|:||:||||..|:..:|  ...|.||..||||.||.|.|:|||..|
Human   136 TNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYC 200

  Fly   205 KKNGILVTAFSPLG---RHNAELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPLPKSS 266
            :..||:|||:||||   |..|:...|:.:.|.:::|||.|:||:.|||:||:.::...:.:|||.
Human   201 QSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSV 265

  Fly   267 NPKRIEENFNVFDFKLDAEDHAILDSYHNGERVAHARQAIKSKYYPFN 314
            .|:||.|||.||||:|.::|...|.||:...||.........|.|||:
Human   266 TPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPFH 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	ARA1	5..298	CDD:223729	144/290 (50%)
		Tas	12..299	CDD:223739	144/291 (49%)
AKR1B1	NP_001619.1	AKR_AKR1B1-19	10..316	CDD:381333	149/306 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1770
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.760