Protein Alignment CG12766 and Akr1c14

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_612556.1
• Gene: Akr1c14 / 191574
• RGDID: 708361
• Length: 322
• Species: Rattus norvegicus
• Alignment Length: 311
• Identity: 132/311 - (42%)
• Similarity: 182/311 - (58%)
• Gaps: 11/311 - (3%)

  Fly    12 NDGTHIQGIGLGTFAS---TEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVIK 73
            |||..|..:|.||...   .:.:..:|...|||.|:||.|:||.|..|.|||.|:|.||.:|.:|
  Rat    11 NDGNFIPVLGFGTTVPEKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEEVGQAIRSKIEDGTVK 75

  Fly    74 REDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEVE 138
            |||||.|:|||..||.||.|.....||||:..|||||||:||:|.:.: .|| ...|:|.:|::.
  Rat    76 REDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMALQ-PGD-IFFPRDEHGKLL 138

  Fly   139 LVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLL--ANCKIKPIHNQIEVHPALDQKKLI 201
            ...:|..|||.||||..|.||.|||||||||..||.|:|  ...|.||:.||:|.|..|:|.|::
  Rat   139 FETVDICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILNKPGLKYKPVCNQVECHLYLNQSKML 203

  Fly   202 ALCKKNGILVTAFSPLGRHN----AELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPL 262
            ..||...|::.::..||...    .:.::|..:.|..:.|||.||.::.|.|.:||.::.|.:||
  Rat   204 DYCKSKDIILVSYCTLGSSRDKTWVDQKSPVLLDDPVLCAIAKKYKQTPALVALRYQLQRGVVPL 268

  Fly   263 PKSSNPKRIEENFNVFDFKLDAEDHAILDSYHNGERVAHARQAIKSKYYPF 313
            .:|.|.|||:|...||:|:|.:||...||..:...|..:|:.......:||
  Rat   269 IRSFNAKRIKELTQVFEFQLASEDMKALDGLNRNFRYNNAKYFDDHPNHPF 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	128/295 (43%)
Akr1c14	NP_612556.1	AKR_AKR1C1-35	7..308	CDD:381334	129/298 (43%)