DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12766 and C07D8.6

DIOPT Version :9

Sequence 1:	NP_647839.1	Gene:	CG12766 / 38462	FlyBaseID:	FBgn0035476	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_509242.1	Gene:	C07D8.6 / 180997	WormBaseID:	WBGene00015565	Length:	317	Species:	Caenorhabditis elegans

Alignment Length:	303	Identity:	118/303 - (38%)
Similarity:	176/303 - (58%)	Gaps:	26/303 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KHNDGTHIQGIGLGTFASTEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVIKR 74
            |.::|..:..|||||:.|:..:...||..|:..|||.||||..|.||..:|.|:::.:.|||:||
Worm     9 KLSNGVEMPVIGLGTWQSSPAEVITAVKTAVKAGYRLIDTASVYQNEEAIGTAIKELLEEGVVKR 73

  Fly    75 EDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEVEL 139
            |::|||||.|.:...|.::|...|::||.:.|:||||||.|.|.::     |:.:.:.....||
Worm    74 EELFITTKAWTHELAPGKLEGGLRESLKKLQLEYVDLYLAHMPAAF-----NDDMSEHIASPVE- 132

  Fly   140 VDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLLANCKIKPIHN-QIEVHPALDQKKLIAL 203
                  |.|...:.:...||.|::||||:|.:|::|.|| ..:.|:|| |:|:|....|...:..
Worm   133 ------DVWRQFDAVYKAGLAKAVGVSNWNNDQISRALA-LGLTPVHNSQVELHLYFPQHDHVDF 190

  Fly   204 CKKNGILVTAFSPL---GRHNAELRT---------PTFMYDGKVQAIADKYNKSIAQVVIRYVIE 256
            |||:.|.||:::.|   ||.|..|.|         |:.:.|..|.|:|:|.:|:.|||::||.::
Worm   191 CKKHNISVTSYATLGSPGRVNFTLPTGQKLDWAPAPSDLQDQNVLALAEKTHKTPAQVLLRYALD 255

  Fly   257 LGTIPLPKSSNPKRIEENFNVFDFKLDAEDHAILDSYHNGERV 299
            .|...||||....||:|||.||||.|..||.|.|:...|.:|:
Worm   256 RGCAILPKSIQENRIKENFEVFDFSLTEEDIAKLEESKNSQRL 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	ARA1	5..298	CDD:223729	117/300 (39%)
CG12766	NP_647839.1	Tas	12..299	CDD:223739	116/299 (39%)
C07D8.6	NP_509242.1	AKR_AKR1G1_CeAKR	5..301	CDD:381380	118/303 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166099
Domainoid	1	1.000	211	1.000	Domainoid score	I1629
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		mtm4839
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.660