Protein Alignment CG12766 and AKR1C2

DIOPT Version :9

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_001345.1
• Gene: AKR1C2 / 1646
• HGNCID: 385
• Length: 323
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 135/314 - (42%)
• Similarity: 185/314 - (58%)
• Gaps: 11/314 - (3%)

  Fly    10 KHNDGTHIQGIGLGTFASTE---GDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGV 71
            |.|||..:..:|.||:|..|   .....||..||:.|:.|||:|:.|.||.:||.|:|.|||:|.
Human     9 KLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGS 73

  Fly    72 IKREDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGE 136
            :||||||.|:|||.|.|.||.|..|..::|||:.||||||||||:|.|.|  ...|:||||.||:
Human    74 VKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK--PGEEVIPKDENGK 136

  Fly   137 VELVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLL--ANCKIKPIHNQIEVHPALDQKK 199
            :....:|...||.||||..|.||.|||||||||...|..:|  ...|.||:.||:|.||..:|:|
Human   137 ILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRK 201

  Fly   200 LIALCKKNGILVTAFSPLGRHNAE----LRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTI 260
            |:..||...|::.|:|.||.|..|    ..:|..:.|..:.|:|.|:.::.|.:.:||.::.|.:
Human   202 LLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVV 266

  Fly   261 PLPKSSNPKRIEENFNVFDFKLDAEDHAILDSYHNGERVAHARQAIKSKYYPFN 314
            .|.||.|.:||.:|..||:|:|.:|:...:|..:...|............|||:
Human   267 VLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	ARA1	5..298	CDD:223729	131/296 (44%)
		Tas	12..299	CDD:223739	130/295 (44%)
AKR1C2	NP_001345.1	AKR_AKR1C1-35	6..308	CDD:381334	132/300 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.730