Protein Alignment CG12766 and Akr1b8

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_032038.1
• Gene: Akr1b8 / 14187
• MGIID: 107673
• Length: 316
• Species: Mus musculus
• Alignment Length: 300
• Identity: 135/300 - (45%)
• Similarity: 188/300 - (62%)
• Gaps: 7/300 - (2%)

  Fly    20 IGLGTFASTEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVIKREDIFITTKLW 84
            :||||:.|.....:.||..|||.||||||.||.|.||.|||.|:::||.|..::|||:||.:|||
Mouse    16 VGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIKEKAVQREDLFIVSKLW 80

  Fly    85 CNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEVELVDIDYLDTWG 149
            ....|.:.::.|.:|||.::.|||:||||||||  ...:...||.|||..|.:......:|:.|.
Mouse    81 PTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWP--QGLQPGKELFPKDDQGRILTSKTTFLEAWE 143

  Fly   150 AMEKLVDLGLTKSIGVSNFNEEQLTRLL--ANCKIKPIHNQIEVHPALDQKKLIALCKKNGILVT 212
            .||:|||.||.|::||||||..|:.|||  ...|.||:.||:|.||.|.|:|||..|...||.||
Mouse   144 GMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHSKGISVT 208

  Fly   213 AFSPLG---RHNAELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPLPKSSNPKRIEEN 274
            |:||||   |.:|:...|:.:.|.|::.||.|:.|:.|||:||:.|:...:.:|||..|.||:||
Mouse   209 AYSPLGSPDRPSAKPEDPSLLEDPKIKEIAAKHEKTSAQVLIRFHIQRNVVVIPKSVTPSRIQEN 273

  Fly   275 FNVFDFKLDAEDHAILDSYHNGERVAHARQAIKSKYYPFN 314
            ..||||:|..|:.|.:.|::...|.....:.:..:.||::
Mouse   274 IQVFDFQLSDEEMATILSFNRNWRACLLPETVNMEEYPYD 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	132/283 (47%)
Akr1b8	NP_032038.1	AKR_AKR1B1-19	10..316	CDD:381333	135/299 (45%)