Protein Alignment CG12766 and Akr1c14

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_598833.1
• Gene: Akr1c14 / 105387
• MGIID: 2145458
• Length: 323
• Species: Mus musculus
• Alignment Length: 311
• Identity: 130/311 - (41%)
• Similarity: 182/311 - (58%)
• Gaps: 11/311 - (3%)

  Fly    12 NDGTHIQGIGLGTFAS---TEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVIK 73
            |||..|..:|.||...   .:.:..:|...|||.|:||.|:||.|..|.|||.|:|.||.:|.:|
Mouse    11 NDGHFIPALGFGTTVPDKVPKDELIKATKIAIDTGFRHFDSAYLYQIEEEVGQAIRSKIEDGTVK 75

  Fly    74 REDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEVE 138
            |||||.|:|||..||.||.|.....|||||..|||||||:||:|.:.: .|| :|.|:|.:|::.
Mouse    76 REDIFYTSKLWSTFHRPELVRSCLEKTLKNAQLDYVDLYIIHFPMALQ-PGD-KLFPRDEHGKLL 138

  Fly   139 LVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLL--ANCKIKPIHNQIEVHPALDQKKLI 201
            ...:|..|||.||||..|.||.|||||||||..||..:|  ...|.||:.||:|.|..|:|.:::
Mouse   139 AEAVDLCDTWEAMEKCKDAGLAKSIGVSNFNFRQLETILNKPGLKYKPVCNQVECHLYLNQSQML 203

  Fly   202 ALCKKNGILVTAFSPLGRHNAEL----RTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPL 262
            ..||...|::.::..||....::    ::|..:.|..:.|:|:||.::.|.:.|||.::.|.:.|
Mouse   204 DYCKSKDIILVSYCTLGSSRDKIWVDQKSPVLLDDPVLCAMANKYKQTPALIAIRYQLQRGIVVL 268

  Fly   263 PKSSNPKRIEENFNVFDFKLDAEDHAILDSYHNGERVAHARQAIKSKYYPF 313
            .:|...|||:|...||:|:|.:||..:||..|...|...|........:||
Mouse   269 TRSFKEKRIKEFMKVFEFQLASEDMKVLDGLHRNLRYNTASYFDDHPNHPF 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	126/295 (43%)
Akr1c14	NP_598833.1	AKR_AKR1C1-35	6..308	CDD:381334	127/298 (43%)