Protein Alignment CG12766 and AKR1A1

DIOPT Version :9

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_001189342.1
• Gene: AKR1A1 / 10327
• HGNCID: 380
• Length: 325
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 126/308 - (40%)
• Similarity: 187/308 - (60%)
• Gaps: 15/308 - (4%)

  Fly    20 IGLGTFASTEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEG-VIKREDIFITTKL 83
            |||||:.|..|..:.||.:|:.|||||||.|..||||.|:|.|:::.:..| .:.||::|:|:||
Human    17 IGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKL 81

  Fly    84 WCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEVELVDIDYLDTW 148
            |...|.||.||.|.||||.::.|:|:||||:|||:::: ||||. .||:|:|.:......|.:||
Human    82 WNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFE-RGDNP-FPKNADGTICYDSTHYKETW 144

  Fly   149 GAMEKLVDLGLTKSIGVSNFNEEQLTRLLANCKIKPIHNQIEVHPALDQKKLIALCKKNGILVTA 213
            .|:|.||..||.:::|:||||..|:..:|:...::|...|:|.||.|.|.:|||.|:..|:.|||
Human   145 KALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTA 209

  Fly   214 FSPLGRHNAELR---TPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPLPKSSNPKRIEENF 275
            :||||..:...|   .|..:.:..|.|:|:||.:|.||:::|:.::...|.:|||..|.||.:|.
Human   210 YSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNI 274

  Fly   276 NVFDFKLDAEDHAILDSYHNGERVAHARQAIKSK---------YYPFN 314
            .||||....|:...|::.:...|.......:..|         .||||
Human   275 KVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPFN 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	ARA1	5..298	CDD:223729	120/281 (43%)
		Tas	12..299	CDD:223739	120/282 (43%)
AKR1A1	NP_001189342.1	ARA1	6..303	CDD:223729	121/287 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1770
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.720