DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sc2 and CER10

DIOPT Version :9

Sequence 1:	NP_647836.2	Gene:	Sc2 / 38457	FlyBaseID:	FBgn0035471	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_191096.1	Gene:	CER10 / 824702	AraportID:	AT3G55360	Length:	310	Species:	Arabidopsis thaliana

Alignment Length:	321	Identity:	121/321 - (37%)
Similarity:	171/321 - (53%)	Gaps:	45/321 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EILNAKNSKPYGKVKVPSGATPIGDLRALIHK------------TLKQTPHANRQSLRLELKGKS 56
            |:|.|       .:.:|..|| :.||:...||            ||..||.:..:.:.|..| ||
plant    12 EVLKA-------PLDLPDSAT-VADLQEAFHKRAKKFYPSRQRLTLPVTPGSKDKPVVLNSK-KS 67

  Fly    57 LKDTDTLESLSLRSGDKIYVKDLGPQIGWKTVFLAEYAGPLIVYLIFYFRPE---LVYGKAASLP 118
            ||:.....:.||    .:..||||.|:.::|:|..||.|||::|.:||:.|.   |.||:...:.
plant    68 LKEYCDGNNNSL----TVVFKDLGAQVSYRTLFFFEYLGPLLIYPVFYYFPVYKFLGYGEDCVIH 128

  Fly   119 ISLTTHIAAGCYTVHYVKRLLETIFVHRFSHATMPLRNLFKNCTYYWGFTAYVSYHVNHPQFTSP 183
            ...|..:...|:  ||.||:|||.|||||||||.|:.|:|:||.|||.|.||::|:||||.:|..
plant   129 PVQTYAMYYWCF--HYFKRILETFFVHRFSHATSPIGNVFRNCAYYWSFGAYIAYYVNHPLYTPV 191

  Fly   184 CMCTVWGALGAFALCELGNFSVHIALRNLRPPGTKVRKIPVADGNPLTK--LFDLVSCPNYTYEI 246
            ....:....|...:|::.||..||.|:|||.|..       |.|..:.:  ||::|:|.|||.||
plant   192 SDLQMKIGFGFGLVCQVANFYCHILLKNLRDPSG-------AGGYQIPRGFLFNIVTCANYTTEI 249

  Fly   247 GAWVSFSVLTSCLAAYLFAFAGAFQMTIWALAKHRNYKKEF--KD----YPRQRRSIFPFV 301
            ..|:.|::.|..:|.|:|....|..||.|||.||...:|.|  ||    |||:...:.||:
plant   250 YQWLGFNIATQTIAGYVFLAVAALIMTNWALGKHSRLRKIFDGKDGKPKYPRRWVILPPFL 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sc2	NP_647836.2	Tsc13_N	3..79	CDD:176396	23/86 (27%)
		PLN02560	15..299	CDD:178174	116/306 (38%)
		PEMT	150..302	CDD:304400	64/160 (40%)
CER10	NP_191096.1	PLN02560	1..310	CDD:178174	120/319 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	116	1.000	Domainoid score	I1991
eggNOG	1	0.900	-	-		E1_KOG1639
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H36231
Inparanoid	1	1.050	187	1.000	Inparanoid score	I1404
OMA	1	1.010	-	-		QHG53957
OrthoDB	1	1.010	-	-		D720263at2759
OrthoFinder	1	1.000	-	-		FOG0001630
OrthoInspector	1	1.000	-	-		oto3377
orthoMCL	1	0.900	-	-		OOG6_102127
Panther	1	1.100	-	-	LDO	PTHR10556
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1032
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840