DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ubi-p63E and UBC

DIOPT Version :9

Sequence 1:	NP_001261383.1	Gene:	Ubi-p63E / 38456	FlyBaseID:	FBgn0003943	Length:	763	Species:	Drosophila melanogaster
Sequence 2:	NP_066289.3	Gene:	UBC / 7316	HGNCID:	12468	Length:	685	Species:	Homo sapiens

Alignment Length:	685	Identity:	684/685 - (99%)
Similarity:	685/685 - (100%)	Gaps:	0/685 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 141
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human     1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 65

  Fly   142 TLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGR 206
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human    66 TLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGR 130

  Fly   207 TLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRL 271
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human   131 TLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRL 195

  Fly   272 IFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQD 336
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human   196 IFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQD 260

  Fly   337 KEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSD 401
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human   261 KEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSD 325

  Fly   402 TIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTG 466
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human   326 TIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTG 390

  Fly   467 KTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRG 531
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human   391 KTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRG 455

  Fly   532 GMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKE 596
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human   456 GMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKE 520

  Fly   597 STLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDG 661
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human   521 STLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDG 585

  Fly   662 RTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQR 726
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human   586 RTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQR 650

  Fly   727 LIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGI 761
            ||||||||||||||||||||||||||||||||||:
Human   651 LIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGV 685

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubi-p63E	NP_001261383.1	Ubiquitin	1..76	CDD:176398
		UBQ	1..72	CDD:214563
		Ubiquitin	77..152	CDD:176398	74/74 (100%)
		UBQ	77..148	CDD:214563	70/70 (100%)
		Ubiquitin	153..228	CDD:176398	74/74 (100%)
		UBQ	153..224	CDD:214563	70/70 (100%)
		Ubiquitin	229..304	CDD:176398	74/74 (100%)
		UBQ	229..300	CDD:214563	70/70 (100%)
		Ubiquitin	305..380	CDD:176398	74/74 (100%)
		UBQ	305..376	CDD:214563	70/70 (100%)
		Ubiquitin	381..456	CDD:176398	74/74 (100%)
		UBQ	381..452	CDD:214563	70/70 (100%)
		Ubiquitin	457..532	CDD:176398	74/74 (100%)
		UBQ	457..528	CDD:214563	70/70 (100%)
		Ubiquitin	533..608	CDD:176398	74/74 (100%)
		UBQ	533..604	CDD:214563	70/70 (100%)
		Ubiquitin	609..684	CDD:176398	74/74 (100%)
		UBQ	609..680	CDD:214563	70/70 (100%)
		Ubiquitin	685..760	CDD:176398	74/74 (100%)
		UBQ	685..756	CDD:214563	70/70 (100%)
UBC	NP_066289.3	Ubl_ubiquitin	1..76	CDD:340501	74/74 (100%)
		Ubl_ubiquitin	77..152	CDD:340501	74/74 (100%)
		Ubl_ubiquitin	153..228	CDD:340501	74/74 (100%)
		Ubl_ubiquitin	229..304	CDD:340501	74/74 (100%)
		Ubl_ubiquitin	305..380	CDD:340501	74/74 (100%)
		Ubl_ubiquitin	381..456	CDD:340501	74/74 (100%)
		Ubl_ubiquitin	457..532	CDD:340501	74/74 (100%)
		Ubl_ubiquitin	533..608	CDD:340501	74/74 (100%)
		Ubl_ubiquitin	609..684	CDD:340501	74/74 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147389
Domainoid	1	1.000	143	1.000	Domainoid score	I4649
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H128418
Inparanoid	1	1.050	1326	1.000	Inparanoid score	I148
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1536766at2759
OrthoFinder	1	1.000	-	-		FOG0000540
OrthoInspector	1	1.000	-	-		oto91065
orthoMCL	1	0.900	-	-		OOG6_100667
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1586
SonicParanoid	1	1.000	-	-		X1758
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	12	11.830