DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ubi-p63E and ubi4

DIOPT Version :9

Sequence 1:	NP_001261383.1	Gene:	Ubi-p63E / 38456	FlyBaseID:	FBgn0003943	Length:	763	Species:	Drosophila melanogaster
Sequence 2:	NP_595409.1	Gene:	ubi4 / 2541030	PomBaseID:	SPBC337.08c	Length:	382	Species:	Schizosaccharomyces pombe

Alignment Length:	381	Identity:	365/381 - (95%)
Similarity:	376/381 - (98%)	Gaps:	0/381 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 65
            ||||||||||||||||||.||||:|||:|||||||||||||||||||||||||||||||||||||
pombe     1 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 65

  Fly    66 TLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGR 130
            |||||||||||||||||||||||||||||.||||:|||:||||||||||||||||||||||||||
pombe    66 TLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGR 130

  Fly   131 TLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRL 195
            ||||||||||||||||||||||||||||||||||||||||.||||:|||:|||||||||||||||
pombe   131 TLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRL 195

  Fly   196 IFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQD 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||.||||:|||:||||
pombe   196 IFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQD 260

  Fly   261 KEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSD 325
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.||
pombe   261 KEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSD 325

  Fly   326 TIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGM 381
            ||:|||:||||||||||||||||||||||||||||||||||||||||||||||||:
pombe   326 TIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGL 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubi-p63E	NP_001261383.1	Ubiquitin	1..76	CDD:176398	71/74 (96%)
		UBQ	1..72	CDD:214563	67/70 (96%)
		Ubiquitin	77..152	CDD:176398	71/74 (96%)
		UBQ	77..148	CDD:214563	67/70 (96%)
		Ubiquitin	153..228	CDD:176398	71/74 (96%)
		UBQ	153..224	CDD:214563	67/70 (96%)
		Ubiquitin	229..304	CDD:176398	71/74 (96%)
		UBQ	229..300	CDD:214563	67/70 (96%)
		Ubiquitin	305..380	CDD:176398	71/74 (96%)
		UBQ	305..376	CDD:214563	67/70 (96%)
		Ubiquitin	381..456	CDD:176398	0/1 (0%)
		UBQ	381..452	CDD:214563	0/1 (0%)
		Ubiquitin	457..532	CDD:176398
		UBQ	457..528	CDD:214563
		Ubiquitin	533..608	CDD:176398
		UBQ	533..604	CDD:214563
		Ubiquitin	609..684	CDD:176398
		UBQ	609..680	CDD:214563
		Ubiquitin	685..760	CDD:176398
		UBQ	685..756	CDD:214563
ubi4	NP_595409.1	Ubiquitin	1..76	CDD:176398	71/74 (96%)
		UBQ	1..72	CDD:214563	67/70 (96%)
		Ubiquitin	77..152	CDD:176398	71/74 (96%)
		UBQ	77..148	CDD:214563	67/70 (96%)
		Ubiquitin	153..228	CDD:176398	71/74 (96%)
		UBQ	153..224	CDD:214563	67/70 (96%)
		Ubiquitin	229..304	CDD:176398	71/74 (96%)
		UBQ	229..300	CDD:214563	67/70 (96%)
		Ubiquitin	305..380	CDD:176398	71/74 (96%)
		UBQ	305..376	CDD:214563	67/70 (96%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	138	1.000	Domainoid score	I1228
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	709	1.000	Inparanoid score	I98
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000540
OrthoInspector	1	1.000	-	-		otm47082
orthoMCL	1	0.900	-	-		OOG6_100667
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1586
SonicParanoid	1	1.000	-	-		X1758
TreeFam	1	0.960	-	-
	11	10.750