Protein Alignment Ccz1 and CCZ1

DIOPT Version :10

• Sequence 1: NP_647835.1
• Gene: Ccz1 / 38455
• FlyBaseID: FBgn0035470
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_009689.3
• Gene: CCZ1 / 852428
• SGDID: S000000335
• Length: 704
• Species: Saccharomyces cerevisiae
• Alignment Length: 453
• Identity: 85/453 - (18%)
• Similarity: 154/453 - (33%)
• Gaps: 151/453 - (33%)

  Fly    12 LRSFYI--FNSTFGQVEGEEHKKVLFYH--------PNDIELNTKIKDVGLSEAIIRFTGTFTSE 66
            :|..||  |:.:....|.:..|::|.:|        |:   ||.|:..:|:.:.|...|.:..::
Yeast     1 MRLHYITVFDPSRSTNENDTFKQLLLFHYFGTTDSIPS---LNEKLSIIGVIQGIWSLTSSCVNK 62

  Fly    67 D--DCQALHTQKTTQLF-YQPEPGYWLVLVLNVPKEVRLKEGVEVADYRGAEISDRIYRAILRQC 128
            |  |.:.:.......:| .:.|..:::.|.::           .::|.:.| |..:...|.|...
Yeast    63 DGEDLEKIIELNNDIIFCIKVESRFFISLAIS-----------NISDDQSA-IPLQYLSAYLWLS 115

  Fly   129 YQMFRFQNGCFSSCGSEEPNPDKRR--ELLCQKLLQFYDQHLTNLRD----------PAQCDIID 181
            |:.|:..||.||..     |.|.|:  :||.:.::.|::....||..          |......:
Yeast   116 YRFFKLLNGSFSGF-----NKDFRKLTDLLNEFVIPFWNDIYLNLETVTNRSFTVMWPGFYKRAN 175

  Fly   182 MLHS------------------IQYLPLDKTLFL----------------------------RAQ 200
            ..||                  :|.:.|||..:|                            ..:
Yeast   176 FQHSSYNPGEKNNVEESWDAIILQNILLDKKSYLGLKDILVYHLPKRTKAANRESMGTKTYGLVR 240

  Fly   201 NFGTLCETFPDIKESIMLYQEQVLCGGKLSPEDLHCVHSYVVQHVLKVEASSSTIAVSPSLKRSI 265
            ||.:...|.|||  |..||.             |||.:..:..|:|     :..:.....|:  :
Yeast   241 NFTSDLNTLPDI--SNWLYH-------------LHCTYGEISSHIL-----TGNVHFKEELQ--V 283

  Fly   266 SECQVGGFVRSRQKVAGDEHDAVNEEDHPMKVYVTLDKEAKPYYLLIYRALH-ITLCLFLNADQV 329
            .|.|    .|||.....||.::   ::...:.:....:.......|..|.:| :||
Yeast   284 EEEQ----ERSRDTNGRDEEES---QEQQRREHQETTQNNTSELSLSERVIHNVTL--------- 332

  Fly   330 APKQDLYDDLHAYMAPQLTSLARDISSELT--------------KEAVGAAGQDNSSGNSETA 378
             |....||.:|.      .|....:|..|:              ..:..:|.::|.|.:::.|
Yeast   333 -PISFAYDAIHE------VSTTTGVSGSLSMIMDYVPKPHWPFISSSNKSADKNNYSNSNDNA 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ccz1	NP_647835.1	Intu_longin_1	12..137	CDD:436911	27/137 (20%)
		Intu_longin_2	212..344	CDD:465951	26/132 (20%)
		Intu_longin_3	375..472	CDD:436913	1/4 (25%)
CCZ1	NP_009689.3	Intu_longin_1	3..124	CDD:436911	26/135 (19%)