Protein Alignment Ccz1 and ccz-1

DIOPT Version :10

• Sequence 1: NP_647835.1
• Gene: Ccz1 / 38455
• FlyBaseID: FBgn0035470
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_506387.1
• Gene: ccz-1 / 186547
• WormBaseID: WBGene00010283
• Length: 528
• Species: Caenorhabditis elegans
• Alignment Length: 544
• Identity: 123/544 - (22%)
• Similarity: 237/544 - (43%)
• Gaps: 119/544 - (21%)

  Fly    12 LRSFYIFNSTFGQVEGEEHKKVLFYHPNDIELNTKIKDVGLSEAIIRFTGTFTS----------- 65
            |..|::.:...|:.|||||.:|:::||...:|..:.:..|.:||::.||..|.|
 Worm    31 LEFFFVAHPLSGRKEGEEHNRVMYFHPKGEQLERQTEITGFAEAVVNFTENFLSTSRREISERIS 95

  Fly    66 --ED--DCQALHTQKTTQLFYQPEPGYWLVLVLNVPKEVRLKEGVEVADYRGAEISDRIYRAILR 126
              ||  |.:.:.||:|..::.:.|...: :|.:::.|::.|     |:||   .:.....|:||.
 Worm    96 ENEDGFDFRTVTTQRTEHVYIRTEDDQF-ILGVSISKQLSL-----VSDY---PLFQPAIRSILS 151

  Fly   127 QCYQMFRFQNGCFSSCGSEEPNPDKRRELLCQKLLQFYDQHLTNLRDPAQCDIIDMLHSIQYLPL 191
            ..|:|||...|.|||.....|:...:.:   ::|..|:.:::..|: ..:..::|.|..:::|.:
 Worm   152 DAYKMFRMFFGTFSSFIKNVPDDIPKFK---ERLDFFFSKYIPLLK-VHKMPLLDHLGGVEFLRM 212

  Fly   192 DKTLFLRAQN-FGTLCETFPDIKESIMLYQEQVLCGGKLSPEDLHCVHSYVVQHVLKVEASSSTI 255
            ...|:|...: ...|.|.|..|::.:.|||:::|. .:||..||..:..|:..::|     .:|:
 Worm   213 SGPLYLNVVSLLSELREEFQVIEKIMFLYQDKLLY-YQLSKRDLPSLFHYLTHNLL-----PTTL 271

  Fly   256 AVSPSLKRSISECQVGGFVR------SRQKVAGDEHDAVNEEDHPMKVYVTLD------KEAKPY 308
            |  |.|:.|......|.::|      :...:.|||..:|        |::..|      :|...|
 Worm   272 A--PELEHSGRNASKGRYLRGPTDLTTDAPLLGDESLSV--------VHLHSDQGTEFQEELIGY 326

  Fly   309 YLLIYRALHITLCLFL------------------NADQVAPKQD------LYDDLHAYMAPQLTS 349
            .:::||.|:.|:|:|:                  .:.:..|.|:      |..::..::..:|:.
 Worm   327 QMIVYRCLNATVCMFVRNCPANGGLEIRRDSESSQSSRATPSQNGVVSRRLLRNIDQFLETELSQ 391

  Fly   350 LARDISSELTKEAVGAAGQDNSSGNSETAPKYLFINEQSLQHHTNFQRHLPQGLPRNVLSIIADL 414
            :|..|..|:..|....|...:          |::.|..||...::....     |:  |.:.|..
 Worm   392 VASKIGDEIGDEKFPEAPDFH----------YIYFNPSSLSMTSSLSTS-----PK--LPVAASG 439

  Fly   415 ANGSGKAEM------------------ESAPAEEVQVKTTNDYWIVKRRCNYRQYYVIL--CNSK 459
            :|.:.|..:                  |:....|..||:::|:|||.::.|.|...:|:  .|..
 Worm   440 SNSTLKVPLPPVDVNRLVCDTMSNFVSETEEFGECFVKSSSDWWIVIKKVNSRLLVLIIPPSNYT 504

  Fly   460 ATLLDVTQEARRIFEQELTDDVFF 483
            ::|.||..:...|..... :.:||
 Worm   505 SSLADVQSKTATIVRSHF-EAIFF 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ccz1	NP_647835.1	Intu_longin_1	12..137	CDD:436911	39/139 (28%)
		Intu_longin_2	212..344	CDD:465951	35/167 (21%)
		Intu_longin_3	375..472	CDD:436913	24/116 (21%)
ccz-1	NP_506387.1	Intu_longin_1	31..162	CDD:436911	39/139 (28%)
		Intu_longin_2	234..386	CDD:465951	35/167 (21%)
		Intu_longin_3	407..517	CDD:436913	25/126 (20%)