DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Awh and LPXN

DIOPT Version :9

Sequence 1:	NP_001261379.1	Gene:	Awh / 38451	FlyBaseID:	FBgn0013751	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	NP_001137467.1	Gene:	LPXN / 9404	HGNCID:	14061	Length:	391	Species:	Homo sapiens

Alignment Length:	174	Identity:	42/174 - (24%)
Similarity:	60/174 - (34%)	Gaps:	62/174 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CAACGEPISDRFFLEVGGCSWH------AHCL---------------------------RCCMCM 39
            ||:|.:||:.: .:...|.|||      .||.                           ||..|.
Human   157 CASCQKPIAGK-VIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCA 220

  Fly    40 CP-LDR------------------------QQSCFIRERQVYCKADYSKNFGAKCSKCCRGISAS 79
            .| ||:                        .:....::::.||:.|:...|..||..|.|.:..:
Human   221 APILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLEN 285

  Fly    80 DWVRRARELVFHLACFACDQCGRQLSTGEQFALMDDRVLCKAHY 123
              ...|.:.|:|..||.|..|....|||..|.| |.|..|:.||
Human   286 --YLSAMDTVWHPECFVCGDCFTSFSTGSFFEL-DGRPFCELHY 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Awh	NP_001261379.1	LIM1_AWH	8..61	CDD:188759	19/110 (17%)
		LIM2_AWH	69..123	CDD:188765	18/53 (34%)
		Homeobox	152..204	CDD:278475
LPXN	NP_001137467.1	LIM1_Leupaxin	155..209	CDD:188790	11/52 (21%)
		LIM2_Leupaxin	216..267	CDD:188792	7/50 (14%)
		LIM3_Leupaxin	275..327	CDD:188794	20/55 (36%)
		LIM4_Paxillin_like	334..385	CDD:188725
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940