DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Awh and pitx1

DIOPT Version :9

Sequence 1:	NP_001261379.1	Gene:	Awh / 38451	FlyBaseID:	FBgn0013751	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	NP_001035436.3	Gene:	pitx1 / 678598	ZFINID:	ZDB-GENE-060421-3623	Length:	285	Species:	Danio rerio

Alignment Length:	166	Identity:	48/166 - (28%)
Similarity:	72/166 - (43%)	Gaps:	24/166 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 SDEGCDGDGYHKSKTKRVRTTFTEEQLQVLQANFQIDSNPDGQDLERIASVTGLSKRVTQVWFQN 198
            ||:| :.|...|.|.:|.||.||.:|||.|:|.||.:..||....|.||..|.|::...:|||:|
Zfish    45 SDDG-NADDPKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKN 108

  Fly   199 SRARQKK-----HIHAGKNKIREPEGSSFARHINLQLTYSFQNNAQNPMHLNGSKAGLYP----- 253
            .||:.:|     .:...||............:.::..||::.         |.:..||.|
Zfish   109 RRAKWRKRERNQQMDLCKNSYLPQFSGLMQPYDDVYPTYTYN---------NWTNKGLTPAPLST 164

  Fly   254 ---THESSMDELSQDSSVHCMPSEVXLEQSSPARAH 286
               |..:||..|: ..|:...||.:.....:....|
Zfish   165 KNFTFFNSMSPLT-SQSMFSAPSSISSMSMASGMGH 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Awh	NP_001261379.1	LIM1_AWH	8..61	CDD:188759
		LIM2_AWH	69..123	CDD:188765
		Homeobox	152..204	CDD:278475	24/51 (47%)
pitx1	NP_001035436.3	COG5576	8..>126	CDD:227863	32/81 (40%)
		Homeobox	62..114	CDD:278475	24/51 (47%)
		OAR	247..263	CDD:281777
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940