DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Awh and LMO3

DIOPT Version :9

Sequence 1:	NP_001261379.1	Gene:	Awh / 38451	FlyBaseID:	FBgn0013751	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	NP_001230542.1	Gene:	LMO3 / 55885	HGNCID:	6643	Length:	167	Species:	Homo sapiens

Alignment Length:	170	Identity:	48/170 - (28%)
Similarity:	74/170 - (43%)	Gaps:	44/170 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TELRSCAACGEPISDRFFLEVGGCSWHAHCLRCCMCMCPL-DRQQSCFIRERQVYCKA------- 59
            |:.:.||.|...|.||:.|:.....||..||:|..|.|.| :..:.|    ..:|..|
Human     8 TKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEHLKRC----GSIYIHAAHTEIGI 68

  Fly    60 -------------DYSKN------FG--AKCSKCCRGISASDWVRRARELVFHLACFACDQCGRQ 103
                         |:|:.      ||  ..|:.|.:.|.|.:.|.||::.|:||.||||..|.::
Human    69 CVTLEWPLPFVIIDFSQQITIAWLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQR 133

  Fly   104 LSTGEQFALMDDRVLCKAHYLETVEGGTTSSDEGCDGDGY 143
            ...|::|.|.::.:||:..|           :||...:||
Human   134 FCVGDKFFLKNNMILCQTDY-----------EEGLMKEGY 162

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Awh	NP_001261379.1	LIM1_AWH	8..61	CDD:188759	18/73 (25%)
		LIM2_AWH	69..123	CDD:188765	20/53 (38%)
		Homeobox	152..204	CDD:278475
LMO3	NP_001230542.1	LIM	13..>49	CDD:295319	15/35 (43%)
LMO3	NP_001230542.1	LIM2_LMO1_LMO3	99..153	CDD:188775	20/53 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910