DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Awh and lhx8

DIOPT Version :9

Sequence 1:	NP_001261379.1	Gene:	Awh / 38451	FlyBaseID:	FBgn0013751	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	XP_012816489.1	Gene:	lhx8 / 548653	XenbaseID:	XB-GENE-494997	Length:	385	Species:	Xenopus tropicalis

Alignment Length:	248	Identity:	111/248 - (44%)
Similarity:	152/248 - (61%)	Gaps:	13/248 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CAACGEPISDRFFLEVGGCSWHAHCLRCCMCMCPLDRQQSCFIRERQVYCKADYSKNFGAKCSKC 72
            |:.||..|.|::.|:|....||..||.|.:|...|.|..||:|:::.:|||.||.:.:|.:||:|
Frog   104 CSNCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIYCKLDYFRRYGTRCSRC 168

  Fly    73 CRGISASDWVRRARELVFHLACFACDQCGRQLSTGEQFALMDDRVLCKAHY-------LETVEGG 130
            .|.|.|:||||||:..|:|||||||..|.|||||||:|||::::|||:.||       ...||.|
Frog   169 GRHIHATDWVRRAKGNVYHLACFACYSCKRQLSTGEEFALVEEKVLCRVHYDCMLDNLKRAVENG 233

  Fly   131 TTSSDEGC---DGDGYHKSKTKRVRTTFTEEQLQVLQANFQIDSNPDGQDLERIASVTGLSKRVT 192
            ...|.||.   :.|.......||.||:||.:||||:||.|..|:|||.|.|::::..||||:||.
Frog   234 NRVSVEGALLTEQDINQPKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLSERTGLSRRVI 298

  Fly   193 QVWFQNSRARQKKHI---HAGKNKIREPEGSSFARHINLQLTYSFQNNAQNPM 242
            ||||||.|||.|||:   |:....:...:.|..:..:..::|||.......||
Frog   299 QVWFQNCRARHKKHVSPNHSSTTPVTTVQPSRLSPPMLEEMTYSAYVPQDGPM 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Awh	NP_001261379.1	LIM1_AWH	8..61	CDD:188759	21/52 (40%)
		LIM2_AWH	69..123	CDD:188765	34/53 (64%)
		Homeobox	152..204	CDD:278475	32/51 (63%)
lhx8	XP_012816489.1	LIM1_Lhx7_Lhx8	103..158	CDD:188767	22/53 (42%)
		LIM2_Lhx7_Lhx8	165..219	CDD:188769	34/53 (64%)
		Homeobox	258..311	CDD:365835	32/52 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I7980
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H62661
Inparanoid	1	1.050	226	1.000	Inparanoid score	I3409
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1161127at2759
OrthoFinder	1	1.000	-	-		FOG0001821
OrthoInspector	1	1.000	-	-		otm48584
Panther	1	1.100	-	-	LDO	PTHR24208
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	1	1.000	-	-		X1183
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.100