DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Awh and pdlim5

DIOPT Version :9

Sequence 1:	NP_001261379.1	Gene:	Awh / 38451	FlyBaseID:	FBgn0013751	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	XP_012817118.2	Gene:	pdlim5 / 548530	XenbaseID:	XB-GENE-854114	Length:	884	Species:	Xenopus tropicalis

Alignment Length:	148	Identity:	39/148 - (26%)
Similarity:	54/148 - (36%)	Gaps:	34/148 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SCAACGEPISDRFFLEVGG------------------C--------------SWHAHCLRCCMCM 39
            :||.|...:::..|:|..|                  |              :||..|..|..|.
Frog   733 NCAHCKSSMAEMGFVEEKGGLYCEICYEKLFAPECARCQRKILGEVINALKQTWHVSCFVCVACQ 797

  Fly    40 CPLDRQQSCFIRERQVYCKADYSKNFGAKCSKCCRGISASDWVRRARELVFHLACFACDQCGRQL 104
            .|: |.....:.:.:.||:.||...||..|..|...|.|.|....|....:|..||.|..|...|
Frog   798 TPI-RNSVFHLEDGEPYCETDYYSLFGTICHGCEFPIEAGDRFLEALGHTWHNTCFVCTICCENL 861

  Fly   105 STGEQFALMDDRVLCKAH 122
            . |:.|....|::|||.|
Frog   862 E-GQTFFSKKDKLLCKKH 878

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Awh	NP_001261379.1	LIM1_AWH	8..61	CDD:188759	16/84 (19%)
		LIM2_AWH	69..123	CDD:188765	19/54 (35%)
		Homeobox	152..204	CDD:278475
pdlim5	XP_012817118.2	PDZ	10..83	CDD:214570
		PRK14951	<80..216	CDD:237865
		DUF4749	212..320	CDD:406377
		LIM1_ENH	708..759	CDD:188837	6/25 (24%)
		LIM2_Enigma_like	767..818	CDD:188748	10/51 (20%)
		LIM3_ENH	826..880	CDD:188843	19/54 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940