Protein Alignment Awh and LHX8

DIOPT Version :10

• Sequence 1: NP_001261379.1
• Gene: Awh / 38451
• FlyBaseID: FBgn0013751
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: XP_016856805.1
• Gene: LHX8 / 431707
• HGNCID: 28838
• Length: 363
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 115/285 - (40%)
• Similarity: 161/285 - (56%)
• Gaps: 42/285 - (14%)

  Fly     8 CAACGEPISDRFFLEVGGCSWHAHCLRCCMCMCPLDRQQSCFIRERQVYCKADYSKNFGAKCSKC 72
            |.:||..|.|::.|:|....||..||.|.:|...|.|..||:|:::.::||.||.:.:|.:||:|
Human    65 CNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGTRCSRC 129

  Fly    73 CRGISASDWVRRARELVFHLACFACDQCGRQLSTGEQFALMDDRVLCKAHY-------LETVEGG 130
            .|.|.::||||||:..|:|||||||..|.|||||||:|||::::|||:.||       ...||.|
Human   130 GRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHYDCMLDNLKREVENG 194

  Fly   131 TTSSDEGC---DGDGYHKSKTKRVRTTFTEEQLQVLQANFQIDSNPDGQDLERIASVTGLSKRVT 192
            ...|.||.   :.|..|....||.||:||.:||||:||.|..|:|||.|.|:::|..||||:||.
Human   195 NGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVI 259

  Fly   193 QVWFQNSRARQKKHI---HAGKNKI-------------REPEGSSFARHINLQLT--YSFQNNAQ 239
            ||||||.|||.|||:   |:....:             .|...|::.......||  :|:.::..
Human   260 QVWFQNCRARHKKHVSPNHSSSTPVTAVPPSRLSPPMLEEMAYSAYVPQDGTMLTALHSYMDDTH 324

  Fly   240 NPMHL--------------NGSKAG 250
            ..:|:              |||.:|
Human   325 AAVHIHLPGRMWRFQGYSNNGSSSG 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Awh	NP_001261379.1	LIM1_AWH	8..61	CDD:188759	20/52 (38%)
		LIM2_AWH	69..123	CDD:188765	33/53 (62%)
		Homeodomain	149..205	CDD:459649	35/55 (64%)
LHX8	XP_016856805.1	LIM1_Lhx7_Lhx8	64..119	CDD:188767	21/53 (40%)
		LIM2_Lhx7_Lhx8	126..180	CDD:188769	33/53 (62%)
		Homeodomain	216..272	CDD:459649	35/55 (64%)