DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Awh and lhx8a

DIOPT Version :9

Sequence 1:	NP_001261379.1	Gene:	Awh / 38451	FlyBaseID:	FBgn0013751	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	NP_001003980.1	Gene:	lhx8a / 378959	ZFINID:	ZDB-GENE-031008-2	Length:	332	Species:	Danio rerio

Alignment Length:	256	Identity:	113/256 - (44%)
Similarity:	154/256 - (60%)	Gaps:	23/256 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TELRSCAACGEPISDRFFLEVGGCSWHAHCLRCCMCMCPLDRQQSCFIRERQVYCKADYSKNFGA 67
            ||...|.:||..|.|::.|:|....||..||.|.:|...|.|..||:|:|::::||.||.:.:|.
Zfish    46 TEKAICTSCGTEIVDKYLLKVNDMCWHVRCLSCSVCQTSLGRHISCYIKEKEIFCKLDYFRKYGT 110

  Fly    68 KCSKCCRGISASDWVRRARELVFHLACFACDQCGRQLSTGEQFALMDDRVLCKAHY--------- 123
            :|:.|.|.|.::||||||:...:|||||||..|.|||||||:|||:|:||||:.||
Zfish   111 RCAHCGRNIHSNDWVRRAKGNTYHLACFACFSCKRQLSTGEEFALVDERVLCRVHYDCMLDNLKR 175

  Fly   124 -LE-----TVEGGTTSSDEGCDGDGYHKSK-TKRVRTTFTEEQLQVLQANFQIDSNPDGQDLERI 181
             :|     .|||...|..|      .::.| .||.||:||.:||||:||.|..|:|||.|.|:::
Zfish   176 AMENGKGVNVEGAVPSEQE------VNQPKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKL 234

  Fly   182 ASVTGLSKRVTQVWFQNSRARQKKHIHAGKNKIREPEGSSFARHINLQLTYSFQNNAQNPM 242
            |..||||:||.||||||.|||.|||: :..:....|..|..:.|::..|....|..|..|:
Zfish   235 AERTGLSRRVIQVWFQNCRARHKKHV-SPNHSSAAPVSSLQSAHLSPPLIDELQYTAFAPV 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Awh	NP_001261379.1	LIM1_AWH	8..61	CDD:188759	21/52 (40%)
		LIM2_AWH	69..123	CDD:188765	33/53 (62%)
		Homeobox	152..204	CDD:278475	33/51 (65%)
lhx8a	NP_001003980.1	LIM1_Lhx7_Lhx8	50..105	CDD:188767	22/54 (41%)
		LIM2_Lhx7_Lhx8	112..166	CDD:188769	33/53 (62%)
		Homeobox	205..257	CDD:278475	33/51 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	84	1.000	Domainoid score	I8171
eggNOG	1	0.900	-	-		E33208_3BHYC
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H62661
Inparanoid	1	1.050	221	1.000	Inparanoid score	I3522
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1161127at2759
OrthoFinder	1	1.000	-	-		FOG0001821
OrthoInspector	1	1.000	-	-		otm26219
orthoMCL	1	0.900	-	-		OOG6_108984
Panther	1	1.100	-	-	LDO	PTHR24208
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1183
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.830