Protein Alignment Awh and Lhx4

DIOPT Version :10

• Sequence 1: NP_001261379.1
• Gene: Awh / 38451
• FlyBaseID: FBgn0013751
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_001101818.2
• Gene: Lhx4 / 360858
• RGDID: 1308044
• Length: 390
• Species: Rattus norvegicus
• Alignment Length: 325
• Identity: 107/325 - (32%)
• Similarity: 151/325 - (46%)
• Gaps: 69/325 - (21%)

  Fly     4 ELRSCAACGEPISDRFFLEVGGCSWHAHCLRCCMCMCPL-DRQQSCFIRERQVYCKADYSKNFGA 67
            ::..||.|.:.|.|:|.|:|....||:.||:|..|...| ||   ||.|...||||.|:.|.||.
  Rat    26 QIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADR---CFSRAGSVYCKEDFFKRFGT 87

  Fly    68 KCSKCCRGISASDWVRRARELVFHLACFACDQCGRQLSTGEQFALMDD-RVLCKAHYLETVEGGT 131
            ||:.|.:||..:..||:|::.|:||.||||..|.|||:||::|.||:| |::||..| ||.:...
  Rat    88 KCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDY-ETAKQND 151

  Fly   132 TSSDEGCDGDGYHKSKTKRVRTTFTEEQLQVLQANFQIDSNPDGQDLERIASVTGLSKRVTQVWF 196
            .|           ::..||.|||.|.:||:.|:..::....|.....|:::|.|||..||.||||
  Rat   152 DS-----------EAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWF 205

  Fly   197 QNSRARQKK-HIHAGKNK----------------------------------IREPEGSSFARHI 226
            ||.||::|: ...||:::                                  .||.:..|...|.
  Rat   206 QNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGGSKQEKESSAEDCGVSDSELSFREDQILSELGHT 270

  Fly   227 NLQLTYSFQNNAQNPMHLNGSKAGLYPTHESSMDELSQ------DSSVHCMPSEVXLEQSSPARA 285
            |  ..|....:......:|||         .|||...|      |.|.:.:|.......|.|:.|
  Rat   271 N--RIYGNVGDVTGGQLMNGS---------FSMDGTGQSYQDLRDGSPYGIPQSPSSISSLPSHA 324

  Fly   286  285
              Rat   325  324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Awh	NP_001261379.1	LIM1_AWH	8..61	CDD:188759	24/53 (45%)
		LIM2_AWH	69..123	CDD:188765	27/54 (50%)
		Homeodomain	149..205	CDD:459649	25/55 (45%)
Lhx4	NP_001101818.2	LIM1_Lhx4	30..81	CDD:188852	24/53 (45%)
		LIM2_Lhx3_Lhx4	89..144	CDD:188762	27/54 (50%)
		Homeodomain	158..214	CDD:459649	25/55 (45%)