DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Awh and HOXB8

DIOPT Version :9

Sequence 1:	NP_001261379.1	Gene:	Awh / 38451	FlyBaseID:	FBgn0013751	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	NP_076921.1	Gene:	HOXB8 / 3218	HGNCID:	5119	Length:	243	Species:	Homo sapiens

Alignment Length:	175	Identity:	36/175 - (20%)
Similarity:	60/175 - (34%)	Gaps:	46/175 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 ADYSKNFGAKCSKCCRGISASDWVRRARELVFHLACFACDQCGRQLSTGEQFALMDDRVLCKAHY 123
            |.|.:|   .|:..|.|...:              .:..|...||...|.|...:.....||.
Human    67 APYQQN---PCAVACHGDPGN--------------FYGYDPLQRQSLFGAQDPDLVQYADCKL-- 112

  Fly   124 LETVEGGTTSSDEGCDGDGYHKSKT----------------KRVRTTFTEEQLQVLQANFQIDSN 172
                   ..:|..|.:.:|..:|.:                :|.|.|::..|...|:..|..:..
Human   113 -------AAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPY 170

  Fly   173 PDGQDLERIASVTGLSKRVTQVWFQNSRARQKKHIHAGKNKIREP 217
            ...:....::...||::|..::||||.|.:.||.    .||.:.|
Human   171 LTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKE----NNKDKFP 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Awh	NP_001261379.1	LIM1_AWH	8..61	CDD:188759	1/1 (100%)
		LIM2_AWH	69..123	CDD:188765	10/53 (19%)
		Homeobox	152..204	CDD:278475	13/51 (25%)
HOXB8	NP_076921.1	Antp-type hexapeptide	134..139		0/4 (0%)
		Homeobox	150..203	CDD:395001	13/52 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	203..243		4/13 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.030