DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Awh and pax6a

DIOPT Version :9

Sequence 1:	NP_001261379.1	Gene:	Awh / 38451	FlyBaseID:	FBgn0013751	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	XP_009296153.1	Gene:	pax6a / 30567	ZFINID:	ZDB-GENE-990415-200	Length:	459	Species:	Danio rerio

Alignment Length:	176	Identity:	49/176 - (27%)
Similarity:	75/176 - (42%)	Gaps:	39/176 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 EGGTTSSDEGCDGDGYH-----KSKTKRVRTTFTEEQLQVLQANFQIDSNPDGQDLERIASVTGL 187
            |...:.|..|.|.|...     |.|.:|.||:||:||::.|:..|:....||....||:|:...|
Zfish   226 ENTNSISSNGEDSDETQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDL 290

  Fly   188 SKRVTQVWFQNSRARQKKHIHAGKNKIREP--EGSSFARHINLQLTYSFQNNAQNPM-------- 242
            .:...||||.|.||:.::     :.|:|..  :.|:.:.||  .::.||..:...|:
Zfish   291 PEARIQVWFSNRRAKWRR-----EEKLRNQRRQASNSSSHI--PISSSFSTSVYQPIPQPTTPVS 348

  Fly   243 HLNGSKAG------------LYPTHESSMD-----ELSQDSSVHCM 271
            ..:||..|            |.|....:|.     :.||.||..||
Zfish   349 FTSGSMLGRSDTALTNTYSALPPMPSFTMANNLPMQPSQTSSYSCM 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Awh	NP_001261379.1	LIM1_AWH	8..61	CDD:188759
		LIM2_AWH	69..123	CDD:188765
		Homeobox	152..204	CDD:278475	21/51 (41%)
pax6a	XP_009296153.1	PAX	31..169	CDD:128645
		Homeobox	255..307	CDD:306543	21/51 (41%)
		Retinal	341..>459	CDD:330657	12/54 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940