DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Awh and hoxb8a

DIOPT Version :9

Sequence 1:	NP_001261379.1	Gene:	Awh / 38451	FlyBaseID:	FBgn0013751	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	XP_005171620.1	Gene:	hoxb8a / 30343	ZFINID:	ZDB-GENE-990415-108	Length:	246	Species:	Danio rerio

Alignment Length:	169	Identity:	38/169 - (22%)
Similarity:	59/169 - (34%)	Gaps:	44/169 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 CSKCCRGISASDWVRRARELVFHLACFACDQCGRQLSTGEQFALMDDRVLCKAHYLETVEGGTTS 133
            |:..|.|...:              .:..|...||...|.|.|.:.....||   |.|  ||.
Zfish    75 CAVTCHGEPGN--------------FYGYDALQRQTLFGAQDADLVQYSDCK---LAT--GGI-- 118

  Fly   134 SDEGCDGDGYHKSKT----------------KRVRTTFTEEQLQVLQANFQIDSNPDGQDLERIA 182
               |.:.|...:|.:                :|.|.|::..|...|:..|..:.....:....::
Zfish   119 ---GDETDNTEQSPSPTQLFPWMRPQVAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVS 180

  Fly   183 SVTGLSKRVTQVWFQNSRARQKKHIHAGKNKIREPEGSS 221
            ...||::|..::||||.|.:.||.    .||.:.|...|
Zfish   181 HALGLTERQVKIWFQNRRMKWKKE----NNKDKFPSSKS 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Awh	NP_001261379.1	LIM1_AWH	8..61	CDD:188759
		LIM2_AWH	69..123	CDD:188765	11/53 (21%)
		Homeobox	152..204	CDD:278475	13/51 (25%)
hoxb8a	XP_005171620.1	Homeobox	150..202	CDD:278475	13/51 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030