Protein Alignment Awh and Lmx1a

DIOPT Version :10

• Sequence 1: NP_001261379.1
• Gene: Awh / 38451
• FlyBaseID: FBgn0013751
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_001099437.2
• Gene: Lmx1a / 289201
• RGDID: 1304784
• Length: 382
• Species: Rattus norvegicus
• Alignment Length: 296
• Identity: 100/296 - (33%)
• Similarity: 142/296 - (47%)
• Gaps: 57/296 - (19%)

  Fly     8 CAACGEPISDRFFLEVGGCSWHAHCLRCCMCMCPLDRQQSCFIRERQVYCKADYSKNFGAKCSKC 72
            |..|...|||||.|.:....||..|::|..|..||  :.:||.|::::|||..|.|.|..||..|
  Rat    35 CEGCQRVISDRFLLRLNDSFWHEQCVQCASCKEPL--ETTCFYRDKKLYCKYHYEKLFAVKCGGC 97

  Fly    73 CRGISASDWVRRARELVFHLACFACDQCGRQLSTGEQFALMDDRVLCKAHY------LETV---- 127
            ...|:.:::|.||::.|:||:||.|..|.|||..|::|.|.:.::|||..|      |..|
  Rat    98 FEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAA 162

  Fly   128 -EGGTTSSDE-----------GCDGDGYHKSKTKRVRTTFTEEQLQVLQANFQIDSNPDGQDLER 180
             :.|.:..:|           |...||....:.||.||..|.:|.:..:|:|::.|.|..:..|.
  Rat   163 SDSGKSDDEESLCKSAHGAGKGASEDGKDHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRET 227

  Fly   181 IASVTGLSKRVTQVWFQNSRARQKKHIHAGKNKIREPEGSSFARHINLQLTYSFQNNAQNPMHL- 244
            :|:.||||.||.||||||.||:.||                .||....|     |.:.||...|
  Rat   228 LAAETGLSVRVVQVWFQNQRAKMKK----------------LARRQQQQ-----QQDQQNTQRLS 271

  Fly   245 ----NGS-KAGL------YPTHESSMDELSQDSSVH 269
                ||| .||:      |.|..:....|:.:.||:
  Rat   272 SAQTNGSGNAGMEGIMNPYTTLPTPQQLLAIEQSVY 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Awh	NP_001261379.1	LIM1_AWH	8..61	CDD:188759	21/52 (40%)
		LIM2_AWH	69..123	CDD:188765	22/53 (42%)
		Homeodomain	149..205	CDD:459649	26/55 (47%)
Lmx1a	NP_001099437.2	LIM1_Lmx1a	35..86	CDD:188756	21/52 (40%)
		LIM2_Lmx1a_Lmx1b	94..148	CDD:188764	22/53 (42%)
		Homeodomain	196..252	CDD:459649	26/55 (47%)