Protein Alignment Awh and FHL1

DIOPT Version :10

• Sequence 1: NP_001261379.1
• Gene: Awh / 38451
• FlyBaseID: FBgn0013751
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_001427698.1
• Gene: FHL1 / 2273
• HGNCID: 3702
• Length: 339
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 58/238 - (24%)
• Similarity: 86/238 - (36%)
• Gaps: 56/238 - (23%)

  Fly     7 SCAACGEPI---------SDRFFLEVGGCSWHAHCLRCCMCMCPLDRQQSCFIRERQVYCKADYS 62
            :|..|.:||         .:||        ||..|.||..|:.|| ..::...::.::.|....:
Human    55 TCVECRKPIGADSKEVHYKNRF--------WHDTCFRCAKCLHPL-ANETFVAKDNKILCNKCTT 110

  Fly    63 KNFGAKCSKCCRGISASDWVRRARELVFHLACFACDQCGRQLSTGEQFALMDDRVLCKAHYLET- 126
            :....||..|.:.|.|.|.....:..|:|..||.|..|.:.:.||..|...:|......|  ||
Human   111 REDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCH--ETK 173

  Fly   127 ------------VEGGTTSSDEGCDGDGY----HKSKTKRVRTTFTEEQLQVLQA--NFQID--- 170
                        ..||.|..|:....|.:    ...|....|.|..|:|...:..  ||...
Human   174 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCA 238

  Fly   171 --SNPDGQDLERIASVTGLSKRVTQVWFQNSRARQKKHIHAGK 211
              .||          :|| .:.|::|....|:||:....| ||
Human   239 GCKNP----------ITG-KRTVSRVSHPVSKARKPPVCH-GK 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Awh	NP_001261379.1	LIM1_AWH	8..61	CDD:188759	15/61 (25%)
		LIM2_AWH	69..123	CDD:188765	15/53 (28%)
		Homeodomain	149..205	CDD:459649	15/62 (24%)
FHL1	NP_001427698.1	None