Protein Alignment Awh and Lmx1b

DIOPT Version :10

• Sequence 1: NP_001261379.1
• Gene: Awh / 38451
• FlyBaseID: FBgn0013751
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: XP_006497809.1
• Gene: Lmx1b / 16917
• MGIID: 1100513
• Length: 408
• Species: Mus musculus
• Alignment Length: 223
• Identity: 89/223 - (39%)
• Similarity: 119/223 - (53%)
• Gaps: 27/223 - (12%)

  Fly     8 CAACGEPISDRFFLEVGGCSWHAHCLRCCMCMCPLDRQQSCFIRERQVYCKADYSKNFGAKCSKC 72
            |..|..||||||.:.|...|||..||:|..|...|  ..||:.|:|::|||.||.:.|.||||.|
Mouse    62 CEGCQRPISDRFLMRVNESSWHEECLQCAACQQAL--TTSCYFRDRKLYCKQDYQQLFAAKCSGC 124

  Fly    73 CRGISASDWVRRARELVFHLACFACDQCGRQLSTGEQFALMDDRVLCKAHY-------------- 123
            ...|:.:::|.||.|.|:||.||.|..|.|||..|::|.|.:.::|||..|
Mouse   125 MEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDE 189

  Fly   124 -----LETVEG------GTTSSDEGCDGDGYHKSKTKRVRTTFTEEQLQVLQANFQIDSNPDGQD 177
                 .|..:|      |..|..:|...||....:.||.||..|.:|.:..:|:|::.|.|..:.
Mouse   190 SDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKV 254

  Fly   178 LERIASVTGLSKRVTQVWFQNSRARQKK 205
            .|.:|:.||||.||.||||||.||:.||
Mouse   255 RETLAAETGLSVRVVQVWFQNQRAKMKK 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Awh	NP_001261379.1	LIM1_AWH	8..61	CDD:188759	24/52 (46%)
		LIM2_AWH	69..123	CDD:188765	24/53 (45%)
		Homeodomain	149..205	CDD:459649	26/55 (47%)
Lmx1b	XP_006497809.1	LIM1_Lmx1b	62..114	CDD:188757	25/53 (47%)
		LIM2_Lmx1a_Lmx1b	121..175	CDD:188764	24/53 (45%)
		Homeodomain	226..282	CDD:459649	26/55 (47%)