Protein Alignment Awh and Isl2

DIOPT Version :10

• Sequence 1: NP_001261379.1
• Gene: Awh / 38451
• FlyBaseID: FBgn0013751
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: XP_006510819.1
• Gene: Isl2 / 104360
• MGIID: 109156
• Length: 370
• Species: Mus musculus
• Alignment Length: 259
• Identity: 94/259 - (36%)
• Similarity: 128/259 - (49%)
• Gaps: 39/259 - (15%)

  Fly     8 CAACGEPISDRFFLEVG-GCSWHAHCLRCCMCMCPLDRQQSCFIRERQVYCKADYSKNFGAKCSK 71
            |..||..|.|:|.|.|. ...|||.||:|..|...||...:||:|:.:.|||.||.:.||.||::
Mouse    38 CVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAQ 102

  Fly    72 CCRGISASDWVRRARELVFHLACFACDQCGRQLSTGEQFALMDDRVLCKAHY---LETVEGGTTS 133
            |..|.|:||.|.|||:.|:|:.||.|..|.|||..|::|:|.:..:||:|.:   ||....|:..
Mouse   103 CQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPR 167

  Fly   134 SDEGCDG-DGYH-------------------KSKTKRVRTTFTEEQLQVLQANFQIDSNPDGQDL 178
            |.....| .|.|                   ..||.||||...|:||..|:..:..:..||....
Mouse   168 SPGPLPGARGLHLPDAGSGRQPSLRTHVHKQAEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMK 232

  Fly   179 ERIASVTGLSKRVTQVWFQNSRARQKK----------HIHAGKNKIREPEGS-----SFARHIN 227
            |::..:||||.||.:|||||.|.:.||          ..|:.|..::...|:     |..||.|
Mouse   233 EQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKASLQGLTGTPLVAGSPIRHEN 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Awh	NP_001261379.1	LIM1_AWH	8..61	CDD:188759	23/53 (43%)
		LIM2_AWH	69..123	CDD:188765	25/53 (47%)
		Homeodomain	149..205	CDD:459649	23/55 (42%)
Isl2	XP_006510819.1	LIM1_Isl	38..92	CDD:188752	23/53 (43%)
		LIM2_Isl2	100..154	CDD:188855	25/53 (47%)
		HOX	202..258	CDD:197696	24/55 (44%)