DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Awh and zfhx3b

DIOPT Version :9

Sequence 1:	NP_001261379.1	Gene:	Awh / 38451	FlyBaseID:	FBgn0013751	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	NP_001352117.1	Gene:	zfhx3b / 100333211	ZFINID:	ZDB-GENE-030131-7577	Length:	3838	Species:	Danio rerio

Alignment Length:	170	Identity:	52/170 - (30%)
Similarity:	74/170 - (43%)	Gaps:	23/170 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 EGGTTSSDEGCDGDGYHKSKTKRVRTTFTEEQLQVLQANFQIDSNPDGQDLERIASVTGLSKRVT 192
            :.||:..:......|....:.||:|||.|.|||::|...:.:||||..:.|:.||...||.|||.
Zfish  2751 KAGTSPGESDSMNSGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVV 2815

  Fly   193 QVWFQNSRARQKKHIHAGKNKIREPEGSSFARHINLQLTYSFQNNAQNPMHL------------- 244
            ||||||:|||::|.........:......|.|.:       |:.......|:
Zfish  2816 QVWFQNTRARERKGQFRAVGPAQAHRRCPFCRAL-------FKAKTALEAHIRSRHWHEAKRAGY 2873

  Fly   245 NGSKAGLYPTHES---SMDELSQDSSVHCMPSEVXLEQSS 281
            |.:.:||.|..|:   .||.|...|..|...|....:.||
Zfish  2874 NLALSGLLPEQEAMQLKMDPLDISSYAHLAQSNNDAQCSS 2913

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Awh	NP_001261379.1	LIM1_AWH	8..61	CDD:188759
		LIM2_AWH	69..123	CDD:188765
		Homeobox	152..204	CDD:278475	29/51 (57%)
zfhx3b	NP_001352117.1	C2H2 Zn finger	734..755	CDD:275368
		C2H2 Zn finger	765..802	CDD:275368
		C2H2 Zn finger	820..837	CDD:275368
		PHA00732	1339..>1391	CDD:177300
		C2H2 Zn finger	1489..1509	CDD:275368
		C2H2 Zn finger	1527..1552	CDD:275368
		C2H2 Zn finger	1555..1574	CDD:275368
		SFP1	<1610..1739	CDD:227516
		C2H2 Zn finger	1672..1696	CDD:275368
		C2H2 Zn finger	1723..1741	CDD:275368
		HOX	2283..2339	CDD:197696
		Homeobox	2383..2436	CDD:306543
		Abdominal-A	2723..2868	CDD:332641	39/123 (32%)
		Homeobox	2775..2827	CDD:306543	29/51 (57%)
		Abdominal-A	3031..>3137	CDD:332641
		Homeobox	3073..3125	CDD:306543
		Herpes_BLLF1	<3228..>3401	CDD:330317
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000