Protein Alignment KRAS and RSR1

DIOPT Version :10

• Sequence 1: XP_047284782.1
• Gene: KRAS / 3845
• HGNCID: 6407
• Length: 227
• Species: Homo sapiens
• Sequence 2: NP_011668.3
• Gene: RSR1 / 853056
• SGDID: S000003384
• Length: 272
• Species: Saccharomyces cerevisiae
• Alignment Length: 282
• Identity: 102/282 - (36%)
• Similarity: 151/282 - (53%)
• Gaps: 65/282 - (23%)

Human     1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYS 65
            |.:|||||:||||||||.||:|.:|..::|.|||||||||||.:.||.:...|:||||||..:::
Yeast     1 MRDYKLVVLGAGGVGKSCLTVQFVQGVYLDTYDPTIEDSYRKTIEIDNKVFDLEILDTAGIAQFT 65

Human    66 AMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL-PSRTVDTKQ 129
            |||:.|:::|.|||.|:::.:.:|.|::...|||:.|:|||:.|||||:|||.|| ..|.:..::
Yeast    66 AMRELYIKSGMGFLLVYSVTDRQSLEELMELREQVLRIKDSDRVPMVLIGNKADLINERVISVEE 130

Human   130 AQDLARSYG-IPFIETSAKTRQRVEDAFYTLVREI------------------------------ 163
            ..:::..:| :||.||||..|..|::.|..|||:|
Yeast   131 GIEVSSKWGRVPFYETSALLRSNVDEVFVDLVRQIIRNEMESVAVKDARNQSQQFSKIESPSTRL 195

Human   164 --------RQYRLKKISK---EEKTPGCVKIKKCIIMGVDDAFYTLVREIRKHKEKMSKDG---- 213
                    :|...|:.||   .:.:.|..|:|:.          |.|.|..|....:.|.|
Yeast   196 PSSAKQDTKQSNNKQSSKGLYNKSSQGQAKVKQS----------TPVNEKHKPSHAVPKSGSSNR 250

Human   214 --------KKKKKKSKTKCVIM 227
                    :|||||:.:.|.|:
Yeast   251 TGISATSQQKKKKKNASTCTIL 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KRAS	XP_047284782.1	H_N_K_Ras_like	3..164	CDD:133338	81/200 (41%)
RSR1	NP_011668.3	RSR1	3..166	CDD:133377	80/162 (49%)