Protein Alignment KRAS and kras

DIOPT Version :9

• Sequence 1: NP_001356715.1
• Gene: KRAS / 3845
• HGNCID: 6407
• Length: 189
• Species: Homo sapiens
• Sequence 2: NP_001349423.1
• Gene: kras / 445289
• ZFINID: ZDB-GENE-040808-67
• Length: 189
• Species: Danio rerio
• Alignment Length: 189
• Identity: 176/189 - (93%)
• Similarity: 184/189 - (97%)
• Gaps: 0/189 - (0%)

Human     1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYS 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish     1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYS 65

Human    66 AMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQA 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||.|..||:|||
Zfish    66 AMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLQSHNVDSKQA 130

Human   131 QDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM 189
            ||||||||||||||||||||||||||||||||||:|||:|:||||||..|:|:|||::|
Zfish   131 QDLARSYGIPFIETSAKTRQRVEDAFYTLVREIREYRLRKLSKEEKTTQCIKLKKCVLM 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KRAS	NP_001356715.1	H_N_K_Ras_like	3..164	CDD:133338	156/160 (98%)
		Effector region	32..40		7/7 (100%)
		Hypervariable region	166..185		12/18 (67%)
kras	NP_001349423.1	H_N_K_Ras_like	3..164	CDD:133338	156/160 (98%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C194326182
Domainoid	1	1.000	313	1.000	Domainoid score	I7035
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37990
Inparanoid	1	1.050	361	1.000	Inparanoid score	I8530
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1259506at2759
OrthoFinder	1	1.000	-	-		FOG0000092
OrthoInspector	1	1.000	-	-		oto49652
orthoMCL	1	0.900	-	-		OOG6_100217
Panther	1	1.100	-	-	LDO	PTHR24070
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1068
SonicParanoid	1	1.000	-	-		X934
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	1	1.500	-	-
	16	16.330