Protein Alignment KRAS and krasl

DIOPT Version :9

• Sequence 1: NP_001356715.1
• Gene: KRAS / 3845
• HGNCID: 6407
• Length: 189
• Species: Homo sapiens
• Sequence 2: XP_004920180.1
• Gene: krasl / 100485959
• XenbaseID: XB-GENE-22063560
• Length: 226
• Species: Xenopus tropicalis
• Alignment Length: 189
• Identity: 185/189 - (97%)
• Similarity: 188/189 - (99%)
• Gaps: 0/189 - (0%)

Human     1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYS 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog     1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYS 65

Human    66 AMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQA 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog    66 AMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQA 130

Human   131 QDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM 189
            ||||||||||||||||||||||||||||||||||||||||:|||||||||||:|||.:|
 Frog   131 QDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKMSKEEKTPGCVKVKKCRVM 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KRAS	NP_001356715.1	H_N_K_Ras_like	3..164	CDD:133338	160/160 (100%)
		Effector region	32..40		7/7 (100%)
		Hypervariable region	166..185		16/18 (89%)
krasl	XP_004920180.1	H_N_K_Ras_like	3..164	CDD:133338	160/160 (100%)
		RAS	16..166	CDD:214541	149/149 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	322	1.000	Domainoid score	I8418
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H37990
Inparanoid	1	1.050	376	1.000	Inparanoid score	I9445
NCBI	1	1.000	-	-
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1259506at2759
OrthoFinder	1	1.000	-	-		FOG0000092
OrthoInspector	1	1.000	-	-		oto158944
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1068
SonicParanoid	1	1.000	-	-		X934
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.000