DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scsalpha1 and Suclg1

DIOPT Version :9

Sequence 1:	NP_001189044.1	Gene:	Scsalpha1 / 38447	FlyBaseID:	FBgn0004888	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	NP_446204.2	Gene:	Suclg1 / 114597	RGDID:	619821	Length:	346	Species:	Rattus norvegicus

Alignment Length:	311	Identity:	222/311 - (71%)
Similarity:	273/311 - (87%)	Gaps:	1/311 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 GVRCNSQYNKTRGNLKLNGDSRVICQGFTGKQGTFHSQQALEYGTKLVGGISPKKGGTQHLGLPV 82
            |:| :..|..:|.|:.::.:::||||||||||||||||||||||||||||.:|.|||.:||||||
  Rat    37 GIR-HGSYTASRKNIYIDKNTKVICQGFTGKQGTFHSQQALEYGTKLVGGTTPGKGGKKHLGLPV 100

  Fly    83 FASVAEAKKATDPHATVIYVPPPGAAAAIIEALEAEIPLIVCITEGVPQHDMVKVKHALISQSKS 147
            |.:|.|||:.|...|:|||||||.|||||.||::|||||:||||||:||.|||:|||.|..|.|:
  Rat   101 FNTVKEAKEKTGATASVIYVPPPFAAAAINEAIDAEIPLVVCITEGIPQQDMVRVKHKLTRQGKT 165

  Fly   148 RLVGPNCPGIIAPEQCKIGIMPGHIHKRGKIGVVSRSGTLTYEAVHQTTEVGLGQTLCVGIGGDP 212
            ||:||||||||.|.:||||||||||||:|:||:||||||||||||||||:|||||:||:||||||
  Rat   166 RLIGPNCPGIINPGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCIGIGGDP 230

  Fly   213 FNGTDFIDCLEVFLKDPETKGIILIGEIGGVAEEKAADYLTEYNSGIKAKPVVSFIAGVSAPPGR 277
            ||||:|||||:||||||.|:||:|||||||.|||.||::|.|:|||.|||||||||||::|||||
  Rat   231 FNGTNFIDCLDVFLKDPATEGIVLIGEIGGHAEENAAEFLKEHNSGPKAKPVVSFIAGITAPPGR 295

  Fly   278 RMGHAGAIISGGKGGANDKIAALEKAGVIVTRSPAKMGHELFKEMKRLELV 328
            |||||||||:||||||.:||:||:.|||||:.|||::|..::||.::.:::
  Rat   296 RMGHAGAIIAGGKGGAKEKISALQSAGVIVSMSPAQLGTCMYKEFEKRKML 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scsalpha1	NP_001189044.1	PTZ00187	22..325	CDD:240307	220/302 (73%)
Suclg1	NP_446204.2	PTZ00187	19..344	CDD:240307	222/307 (72%)
		CoA_binding	53..146	CDD:280747	68/92 (74%)
		Coenzyme A binding. /evidence=ECO:0000255\|HAMAP-Rule:MF_03222	64..67		2/2 (100%)
		Coenzyme A binding. /evidence=ECO:0000255\|HAMAP-Rule:MF_03222	143..145		1/1 (100%)
		Ligase_CoA	199..324	CDD:278948	101/124 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346236
Domainoid	1	1.000	216	1.000	Domainoid score	I2622
eggNOG	1	0.900	-	-		E1_COG0074
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55785
Inparanoid	1	1.050	466	1.000	Inparanoid score	I1472
OMA	1	1.010	-	-		QHG60703
OrthoDB	1	1.010	-	-		D1247548at2759
OrthoFinder	1	1.000	-	-		FOG0002539
OrthoInspector	1	1.000	-	-		otm46021
orthoMCL	1	0.900	-	-		OOG6_100834
Panther	1	1.100	-	-	LDO	PTHR11117
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1662
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770