Protein Alignment PIG-B and Alg12

DIOPT Version :10

• Sequence 1: NP_647832.1
• Gene: PIG-B / 38446
• FlyBaseID: FBgn0035464
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_649939.1
• Gene: Alg12 / 41191
• FlyBaseID: FBgn0037743
• Length: 678
• Species: Drosophila melanogaster
• Alignment Length: 673
• Identity: 127/673 - (18%)
• Similarity: 247/673 - (36%)
• Gaps: 198/673 - (29%)

  Fly    10 ILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQ-------GI--RSYVYPLLIA 65
            ||....|:..:|.|.:...|...:|:..|.:.    ||...:.|       |:  |:::.||:::
  Fly     3 ILIFVTAAAHLVYTPFTKVEESFNLQAMHDIL----YLRNNFTQYDHHDYPGVVPRTFIGPLVVS 63

  Fly    66 -------GLYKILALLQLDSAHLLVVLPRIVQALLSAYSDYRFFV----WTGKRKWALFLILVPW 119
                   .|::.|::.:..:.:::.::  :..|:..|::..|..|    ....|.|...:.:..:
  Fly    64 IISAPFVLLFETLSINKFWAQYVVRLV--LAGAISVAWNSLRQAVTKIYGVEVRLWFTAITITQF 126

  Fly   120 FWFYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAIC------CFLRPTAAVIWLPLSLY 178
            .:.:..:|.|.|.....:...|::|  |..:...   |..||      .|....|..:.:.|.:.
  Fly   127 HFMFYMTRPLPNIFALPIVLFAIAY--WLRDQHK---PFIICSGISILVFRSELALFLGILLVVS 186

  Fly   179 HLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIGSFYGSHPWH 243
            .|||...  ::.:||..:..|:.:....:.:|:::..:|:....|.|.||...|..|.:|:.|:.
  Fly   187 LLRRKVS--IDGLLKVALPAGVCILAATVLVDSFFWRRLLWPEGEVLWYNTVLNKSSNWGTSPFL 249

  Fly   244 WYFSVGLPTVLGINTLPFIFGV-METVKKSEKYPVSKQLLITIFLTLVVLSAVEHKEFRFVSPLL 307
            |||...||..:|.:.:....|| :|        |..:.|:::..|.:::.|.:.|||.||:..:.
  Fly   250 WYFYSALPRAMGASLVLVPIGVALE--------PRIRPLVLSALLFVLLYSILPHKELRFIIYVF 306

  Fly   308 PLCLYVITDALSR-WSIRASSTMLW------------------TTALVILVGNVMPAW-YLSTVH 352
            |:.......|..| |...|.||  |                  |..|:::.|...|.. .||.:|
  Fly   307 PVLNIAAACACQRIWMNSAKST--WHSFLALACGAHLLLNVFITLFLLVISGTNYPGGAALSRLH 369

  Fly   353 ------------------QKGPIELMPKLREIAREY---RDEREH--QANILFLMPCHSTPYYSH 394
                              |.|    :.:..||..|:   :||..:  ||:::         .|:|
  Fly   370 RLEAGTSNVSVHISNLAAQSG----VSRFMEINNEWTYSKDETMNYTQADLV---------AYTH 421

  Fly   395 I------HQNV-----------TMRFLTCEPN---------------------LEKKEQYKDEA- 420
            :      .||.           |:.|:.|..:                     |:|:.....||
  Fly   422 LLVEAKNKQNTELWASLQNEFDTLEFIDCFNSIGIQYNSLLPVRIKTKPCIGILKKRPVAPKEAS 486

  Fly   421 ---DRFFEDPVHWINSHIPMHPLTALPTHVVLFDPL----------------------------- 453
               ::..:...:.:.....:.|:...|.  |:.||.
  Fly   487 KTKEKIAKTKTYPVEKETLLAPVKEFPK--VIGDPKMKSRLQVDADDDDGIVSTVEEMSLELETD 549

  Fly   454 ------AENISVFLR--NYRLLHRIEHAEVTRLEGS------QALVDQWSEALGAQSPNLASLLQ 504
                  ||.|...|:  |::.|..:...:.|:...:      :.:::|...|.|.|..|.::..|
  Fly   550 TEPHAGAETIETPLKEINFQELRTLALGQATKKSRAATKMKIRQIIEQHYRAKGKQIENDSAETQ 614

  Fly   505 NRQSRTG-----RSILVYQRLKK 522
            ..|.:.|     :||:..:::|:
  Fly   615 KTQGKAGLRQSVKSIIKQEKIKE 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-B	NP_647832.1	Glyco_transf_22	5..396	CDD:281842	95/461 (21%)
Alg12	NP_649939.1	PMT_2	3..351	CDD:473917	78/370 (21%)