Protein Alignment IntS10 and Ints10

DIOPT Version :9

• Sequence 1: NP_647830.1
• Gene: IntS10 / 38444
• FlyBaseID: FBgn0035462
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: XP_006509804.1
• Gene: Ints10 / 70885
• MGIID: 1918135
• Length: 763
• Species: Mus musculus
• Alignment Length: 787
• Identity: 181/787 - (22%)
• Similarity: 319/787 - (40%)
• Gaps: 198/787 - (25%)

  Fly     1 MPSQEENELYMVKEAQRLRKSDPCAAMAWIITAKTLYPNAFNLQYEAYLLERDAQNYEEAAKCFS 65
            |.:|.:.| ::|:.|:.|...|..||.||:|||::|||..||:|||.|.:||:|:....|.:...
Mouse     1 MSAQGDCE-FLVQRARELVPQDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTATAGRLLY 64

  Fly    66 AIATNFQNQHTELWQEINSLTNALRNENETTPEHEFYVKMYKHLTPEVQHNIFMHTINHSADNLE 130
            .:..||.:|.. :|:||:.:|:||||::: ..:.:|...:::.|...||..:.:.......:.||
Mouse    65 DMFVNFPDQPV-VWREISIITSALRNDSQ-DKQTQFLRSLFETLPGRVQCEMLLKVTEQCFNTLE 127

  Fly   131 RIYIYILMFNKFPKSAITQAPRLLEMLAEGMKTEP-----DLYQRILVEEVLPM-IQNKPPELSP 189
            |..:.:|:..:||::.:.....|.|.|.|....|.     :.::::.|.:|||: |.|....|..
Mouse   128 RSEMLLLLLRRFPETVVQHGVGLGEALLEAETIEEQDSPVNCFRKLFVCDVLPLIINNHDVRLPA 192

  Fly   190 NLACRLYTSSLEFYLRQI-------------MDESD-----------------------TADAWK 218
            ||..:....:.|||:..:             .|.||                       ..|.|:
Mouse   193 NLLYKYLNKAAEFYINYVTRSTQSENQHQGAQDTSDLMSPSKRSSQKYIIEGLTEKSSHIVDPWE 257

  Fly   219 NIFKVLMICGQMMGWE-------------PFLPFSKHVN------QNVYWEKLVDILSGSPAGSS 264
            .:||:|.:.|....|:             ......:::|      .|.|              .:
Mouse   258 RLFKILNVVGMRCEWQMDKGRRSCSDLLHRMKELCRYMNSFDSEAHNNY--------------KN 308

  Fly   265 QVLFYATTLFIYSLHGYIRNCK---------------LRIED-----ADV-----THV-----LV 299
            |||:....:|..|...|:.:.:               :.:||     .||     .|:     |.
Mouse   309 QVLYSTMLVFFKSAFQYVSSIQPSLFQGPNAPSQVPLILLEDVANVYGDVEIDRSKHIHKKRKLA 373

  Fly   300 EGFMEWSPEGDGSEVPS------MEPPKFSLTTAISPELSKAFLHAAQCWQLLNTDQF-QRDFSQ 357
            ||..:.....|..|..:      :...|..|:.:|  |:.::|..|.:.|:||.:.:| .::|::
Mouse   374 EGREKTMQSSDDEECSAKGRNRHIVVSKADLSNSI--EVLESFKLARESWELLYSLEFLDKEFTR 436

  Fly   358 LMLALPLAP--WISRFLFDLAIYFGHRDEANKLMADMTTQSSLVQSLQILSLNLMQGSMTLQGFQ 420
            :.||.....  |:..||.|:.||.|   :..|.:|.:...::|..|   ||...:.|..||:..:
Mouse   437 ICLAWKTDTWLWLRIFLTDMIIYQG---QYKKAIASLHHLAALQGS---LSQPQITGQGTLEHQR 495

  Fly   421 CILKI------LSELPTTQGQLLENMSL-----------------------KGHRHMVFLPLTRS 456
            .::::      |.|...|..::|:.|..                       || ..:..||.|..
Mouse   496 ALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDGGKPQEEPSKVKPKCRKG-LDLKLLPCTSK 559

  Fly   457 ALVQYCVGAIISRLSRKVFEPNVPDRLLGDILVLQQLNLLNDVLLTQQIFNLIKQRKSFNLRTLS 521
            |::.||:..:::....:.|..:..|..||.::||.|........|..:..:.|.|:.:|......
Mouse   560 AIMPYCLHLMLACFKLRAFTDSRDDMALGHVIVLLQQEWPRGENLFLKAISKICQQGNFQYENFF 624

  Fly   522 TYIINIDLLEELSHIWNSQQEDNFELTSSPNS----------------SGTPTATTV---AGGSQ 567
            :|:.|||:|||.::: .:|:.....|...||.                ||....::|   ..|..
Mouse   625 SYVTNIDMLEEFAYL-RTQEGGKIHLELLPNQGMLINHCRPFGWSLQMSGRDVVSSVPLLPLGPS 688

  Fly   568 SRRIG-----------------------TRGADKGARDEFRAITRQQIARCNENVITLLANFINQ 609
            |..:|                       |||..||.:::||....:|::||.||::.:|..|...
Mouse   689 SPPMGLLQQEFLPVLQPSIQTADRHHTVTRGITKGVKEDFRLAMERQVSRCGENLMAVLHRFCIN 753

  Fly   610 EHLMLAQ 616
            |.::|.|
Mouse   754 EKILLLQ 760

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	162	1.000	Domainoid score	I3971
eggNOG	1	0.900	-	-		E1_28HQX
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10029
Inparanoid	1	1.050	163	1.000	Inparanoid score	I4202
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47437
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008001
OrthoInspector	1	1.000	-	-		oto92326
orthoMCL	1	0.900	-	-		OOG6_108066
Panther	1	1.100	-	-	LDO	PTHR16055
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9053
SonicParanoid	1	1.000	-	-		X5956
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.860