Protein Alignment IntS10 and Ints10

DIOPT Version :10

• Sequence 1: NP_647830.1
• Gene: IntS10 / 38444
• FlyBaseID: FBgn0035462
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: XP_063131280.1
• Gene: Ints10 / 290679
• RGDID: 1304711
• Length: 812
• Species: Rattus norvegicus
• Alignment Length: 743
• Identity: 182/743 - (24%)
• Similarity: 317/743 - (42%)
• Gaps: 163/743 - (21%)

  Fly     1 MPSQEENELYMVKEAQRLRKSDPCAAMAWIITAKTLYPNAFNLQYEAYLLERDAQNYEEAAKCFS 65
            |.:|.:.| ::|:.|:.|...|..||.||:|||::|||..||:|||.|.:||:|:....|.:...
  Rat   103 MSAQGDCE-FLVQRARELVPQDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTATAGRLLY 166

  Fly    66 AIATNFQNQHTELWQEINSLTNALRNENETTPEHEFYVKMYKHLTPEVQHNIFMHTINHSADNLE 130
            .:..||.:|.. :|:||:.:|:||||::: ..:.:|...:::.|...||..:.:.......:.||
  Rat   167 DMFVNFPDQPV-VWREISIITSALRNDSQ-DKQTQFLRSLFETLPGRVQCEMLLKVTEQCFNTLE 229

  Fly   131 RIYIYILMFNKFPKSAITQAPRLLEMLAEGMKTEP-----DLYQRILVEEVLPM-IQNKPPELSP 189
            |..:.:|:..:||::.:.....|.|.|.|....|.     :.::::.|.:|||: |.|....|..
  Rat   230 RSEMLLLLLRRFPETVVQHGVGLGEALLEAETIEEQESPVNCFRKLFVCDVLPLIINNHDVRLPA 294

  Fly   190 NLACRLYTSSLEFYLRQIM-------------DESD-----------------------TADAWK 218
            ||..:....:.|||:..:.             |.||                       ..|.|:
  Rat   295 NLLYKYLNKAAEFYINYVTRSTQLENQHQGAPDTSDLMSPSKRSSQKYIIEGLTEKSSHIVDPWE 359

  Fly   219 NIFKVLMICGQMMGWE-------------PFLPFSKHVNQNVYWEKLVDILSGSPAGS---SQVL 267
            .:||:|.:.|....|:             ......:::|.           ..|.|.:   :|||
  Rat   360 RLFKILNVVGMRCEWQMDKGRRSCSDMLHRMKELCRYMNS-----------FDSEAHTKYKNQVL 413

  Fly   268 FYATTLFIY-SLHGYIRNCK---------------LRIED-----ADV-----THV-----LVEG 301
             |:|.|.:: |...||.:.:               :.:||     .||     .|:     |.||
  Rat   414 -YSTMLVLFKSAFQYISSIQPSLFQGPNAPSQVPLVLLEDVANVYGDVEIDRSKHIHKKRKLAEG 477

  Fly   302 FMEWSPEGDGSEVPS------MEPPKFSLTTAISPELSKAFLHAAQCWQLLNTDQF-QRDFSQLM 359
             .|.:...|..|..:      :...|..|:.:|  |:.::|..|.:.|:||.:.:| .::|:::.
  Rat   478 -REKTMSSDDEECSAKGRNRHIVVSKADLSNSI--EVLESFKLARESWELLYSLEFLDKEFTRIC 539

  Fly   360 LALPLAP--WISRFLFDLAIYFGHRDEANKLMADMTTQSSLVQSLQILSLNLMQGSMTLQGFQCI 422
            ||.....  |:..||.|:.||.|   :..|.:|.:...::|..|   ||...:.|..||:..:.:
  Rat   540 LAWKTDTWLWLRIFLTDMIIYQG---QYKKAIASLHHLAALQGS---LSQPQITGQGTLEHQRAL 598

  Fly   423 LKI------LSELPTTQGQLLENMSL-----------------------KGHRHMVFLPLTRSAL 458
            :::      |.|...|..::|:.|..                       || ..:..||.|..|:
  Rat   599 IQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDGGKSQEEPSKVKPKCRKG-LDLKLLPCTSKAI 662

  Fly   459 VQYCVGAIISRLSRKVFEPNVPDRLLGDILVLQQLNLLNDVLLTQQIFNLIKQRKSFNLRTLSTY 523
            :.||:..:::....:.|..|..|..||.::||.|........|..:..:.|.|:.:|......:|
  Rat   663 MPYCLHLMLACFKLRAFTDNRDDMALGHVIVLLQQEWPRGENLFLKAISKICQQGNFQYENFFSY 727

  Fly   524 IINIDLLEELSHIWNSQQEDNFELTSSPNSSGTPTATTVAGGSQSRRIGTRGADKGARDEFRAIT 588
            :.|||:|||.::: .:|:.....|...||........||          |||..||.:::||...
  Rat   728 VTNIDMLEEFAYL-RTQEGGKIHLELLPNQGMLIKHHTV----------TRGITKGVKEDFRLAM 781

  Fly   589 RQQIARCNENVITLLANFINQEHLMLAQ 616
            .:|::||.||::.:|..|...|.::|.|
  Rat   782 ERQVSRCGENLMVVLHRFCINEKILLLQ 809