Protein Alignment ppk27 and asic1c

DIOPT Version :10

• Sequence 1: NP_647826.2
• Gene: ppk27 / 38440
• FlyBaseID: FBgn0035458
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: XP_021325802.1
• Gene: asic1c / 407670
• ZFINID: ZDB-GENE-040513-3
• Length: 562
• Species: Danio rerio
• Alignment Length: 493
• Identity: 105/493 - (21%)
• Similarity: 174/493 - (35%)
• Gaps: 136/493 - (27%)

  Fly     4 IVTAFNKTVVEYFRKTSLNGFGLLYFIRKRRIQRIFWF--LFISFGILFASYAVFSMVLEFLSYS 66
            |.|||       ..:|.::|....:...|.:.||:||.  |.:..|:||.  ..::.:|..|||.
Zfish    37 ITTAF-------VLRTKVHGLKHAFSPHKSKTQRLFWLLALLVCLGLLFT--WSWNRILYLLSYP 92

  Fly    67 TIADLSELKVLEDEIHFPELKICSGYKFSYRNMLASAHDLVSSQNKSLDYWLNKLSL---LSGYF 128
            .:..:  ..|..:.:.||.:..|:..:....::  :..||..|     .||::.|.|   |:...
Zfish    93 AVTKI--YMVWSNNMTFPAITFCNQNRLRVSSL--TRDDLYYS-----GYWMDILHLNHTLNRQS 148

  Fly   129 DALSVKAENVDDLNSLLDIK----------NISSFLLALTPACESLILKCKLNNIPANCL----- 178
            .::...:.:.:.|..|||..          |.:..:..|....:.::|:|:...  .||.
Zfish   149 VSMLKHSRHRERLLHLLDFSHYSPPPDQSLNTTEMIDRLGHQLQDMLLECRFRG--ENCTYKNFT 211

  Fly   179 -------KLFTLKAYNDGNCCVLRNSNLTGE-LTLFMDSSQIDEY-PLNGN-------------- 220
                   |.:|..:..|||..:......||. |.:.:|..| ||| |:.|:
Zfish   212 PIYTRYGKCYTFNSGLDGNPLLTTLKGGTGNGLEIMLDIQQ-DEYLPVWGDTDETSYEAGIKVQI 275

  Fly   221 ----------------LPGFSLHVPSWQGRVSINPGEMAAVEIEVMELQGNSQLNEYAVEKRACY 269
                            .|||...|...|..:...|..........|:.:               |
Zfish   276 HSQDEPPFIDQLGFGVAPGFQTFVSCQQQLLLYLPPPWGDCRSAPMDSE---------------Y 325

  Fly   270 FSQEGESREKCLHECRIKATLINCQC--VPYPFEFRTQKFGYCTLENIR-CLQ-----LVERNWS 326
            ||.  .|...|..:|..:..|.||.|  |..|.....     ||.|..: |..     |||::..
Zfish   326 FST--YSITACRIDCETRYLLENCNCRMVHMPGTSTV-----CTPEQYKDCADPALDFLVEKDND 383

  Fly   327 PAQCPQCLPLCNQLFYRLNKQILGHLHPWRSELNFKFKTPHR-QRYKT-NIL------------- 376
            ...|.  .| ||..  |..|::.....|.::...:..|..:: ::|.| |||
Zfish   384 YCVCD--TP-CNMT--RYGKELSMVKIPSKASAKYLAKKFNKTEQYITDNILVLDIFFEALNYEK 443

  Fly   377 ------YHWYQMLSNVGGVLGICIGCSFISGFELIYFL 408
                  |....:|.::||.:|:.||.|.::..|:..:|
Zfish   444 IEQKKAYEVAGLLGDIGGQMGLFIGASVLTILEIFDYL 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk27	NP_647826.2	ASC	15..407	CDD:459966	100/479 (21%)
asic1c	XP_021325802.1	ENaC	34..531	CDD:273304	105/493 (21%)