Protein Alignment ppk27 and Asic3

DIOPT Version :10

• Sequence 1: NP_647826.2
• Gene: ppk27 / 38440
• FlyBaseID: FBgn0035458
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: XP_038963092.1
• Gene: Asic3 / 286920
• RGDID: 708578
• Length: 564
• Species: Rattus norvegicus
• Alignment Length: 537
• Identity: 90/537 - (16%)
• Similarity: 161/537 - (29%)
• Gaps: 213/537 - (39%)

  Fly    20 SLNGFGLLYFIRKRRIQRIFWFLFISFGILFASYAVFSMVLEFLSYSTIADLSELKVLEDEIHFP 84
            :::|.|.::......::|..|...:...:....|.|...|..:..:.....|.|.:  ..::.||
  Rat    26 TMHGLGHIFGPGGLTLRRGLWATAVLLSLAAFLYQVAERVRYYGEFHHKTTLDERE--SHQLTFP 88

  Fly    85 ELKICSGYKFSYRNMLASAHDLVSSQNKSLDYWLNKLSLLSGYFDALSVKAENVDDLNSLLDIKN 149
            .:.:|:....  |....:.:||         :|..  :.|.|                  ||...
  Rat    89 AVTLCNINPL--RRSRLTPNDL---------HWAG--TALLG------------------LDPAE 122

  Fly   150 ISSFLLAL--TPA----------------------CESLILKCKLNNIPA---NCLKLFTLKAYN 187
            .:::|.||  .||                      .|.::|.|:....|.   |...:||    .
  Rat   123 HAAYLRALGQPPAPPGFMPSPTFDMAQLYARAGHSLEDMLLDCRYRGQPCGPENFTVIFT----R 183

  Fly   188 DGNCCVLRNSNLTGE-------------LTLFMDSSQIDEYPLNGNLPGFSLHVPSWQGRVSINP 239
            .|.|... ||...|.             |.:.:|..| :||            :|.|:
  Rat   184 MGQCYTF-NSGAHGAELLTTPKGGAGNGLEIMLDVQQ-EEY------------LPIWK------- 227

  Fly   240 GEMAAVEIEV-MELQGNSQLNEYAVEKRACYFSQEGESREKCLHECRIKATLINCQCVPYPFEFR 303
             :|.....|| :.:|.:||....|:::.. :.:..|       |:     |.::||  .....|.
  Rat   228 -DMEETPFEVGIRVQIHSQDEPPAIDQLG-FGAAPG-------HQ-----TFVSCQ--QQQLSFL 276

  Fly   304 TQKFGYCTLEN---------------------------IRCLQLVERNWSPAQC-------PQCL 334
            ...:|.|...:                           |.|....|..:...:|       |...
  Rat   277 PPPWGDCNTASLDPDDFDPEPSDPLGSPRPRPSPPYSLIGCRLACESRYVARKCGCRMMHMPGNS 341

  Fly   335 PLCNQLFY--------------------------RLNKQILGHLHPWRSELNFKFKTPHR-QRYK 372
            |:|:...|                          |..|::.....|.|:...:..:..:| :.|.
  Rat   342 PVCSPQQYKDCASPALDAMLRKDTCVCPNPCATTRYAKELSMVRIPSRASARYLARKYNRSESYI 406

  Fly   373 T-NIL-------------------YHWYQMLSNVGGVLGICIGCSFISGFELIYFL--------- 408
            | |:|                   |...::|.::||.:|:.||.|.::..|::.:|
  Rat   407 TENVLVLDIFFEALNYEAVEQKAAYEVSELLGDIGGQMGLFIGASLLTILEILDYLCEVGKNPRH 471

  Fly   409 --------VFRLWTNYL 417
                    ..:.||.||
  Rat   472 HGEESGHQCLKGWTGYL 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk27	NP_647826.2	ASC	15..407	CDD:459966	85/508 (17%)
Asic3	XP_038963092.1	ENaC	17..547	CDD:273304	90/537 (17%)