Protein Alignment ppk27 and Asic2

DIOPT Version :10

• Sequence 1: NP_647826.2
• Gene: ppk27 / 38440
• FlyBaseID: FBgn0035458
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_037024.2
• Gene: Asic2 / 25364
• RGDID: 2017
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 483
• Identity: 100/483 - (20%)
• Similarity: 169/483 - (34%)
• Gaps: 167/483 - (34%)

  Fly    36 QRIFWFLFI--SFGILFASYAVFSMVLEFLSYSTIADLSELKVLED---EIHFPELKICSG---- 91
            :|..|.|..  |.|:|.:..:  :.:|.:||:.     |..:|..:   ::.||.:.:|:.
  Rat    85 RRALWVLAFCTSLGLLLSWSS--NRLLYWLSFP-----SHTRVHREWSRQLPFPAVTVCNNNPLR 142

  Fly    92 ----------YKFSYRNML---ASAHDLVSS---QNKSLDYWLNKLS-----LLSGYFDALSVKA 135
                      |...:..:|   .:|..|||.   .::....|..||:     |...:|:.:|
  Rat   143 FPRLSKGDLYYAGHWLGLLLPNRTARPLVSELLRGDEPRRQWFRKLADFRLFLPPRHFEGIS--- 204

  Fly   136 ENVDDLNSLLDIKNISSFLLALTPACESLILKCKLNNI---PANCLKLFTL--KAY-----NDGN 190
                           ::|:..|....|.::|.||....   |.|...:||.  |.|     .||.
  Rat   205 ---------------AAFMDRLGHQLEDMLLSCKYRGELCGPHNFSSVFTKYGKCYMFNSGEDGK 254

  Fly   191 CCVLRNSNLTGE-LTLFMDSSQIDEY-PLNGN------------------------------LPG 223
            ..:......||. |.:.:|..| ||| |:.|.                              .||
  Rat   255 PLLTTVKGGTGNGLEIMLDIQQ-DEYLPIWGETEETTFEAGVKVQIHSQSEPPFIQELGFGVAPG 318

  Fly   224 FSLHVPSWQGRVSINP---GEMAAVEIEVMELQGNSQLNEYAVEKRACYFSQEGESREKCLHECR 285
            |...|.:.:.|::..|   ||..:.|:      |......|::              ..|..:|.
  Rat   319 FQTFVATQEQRLTYLPPPWGECRSSEM------GLDFFPVYSI--------------TACRIDCE 363

  Fly   286 IKATLINCQC--VPYPFEFRTQKFGYCTLENIR-CLQ-----LVER--NWSPAQCPQCLPLCNQL 340
            .:..:.||.|  |..|.:     ..:||.|..: |.:     |.|:  |:...:.|     ||
  Rat   364 TRYIVENCNCRMVHMPGD-----APFCTPEQHKECAEPALGLLAEKDSNYCLCRTP-----CN-- 416

  Fly   341 FYRLNKQILGHLHPWRSELNFKFKTPHR-QRY-KTNIL-------------------YHWYQMLS 384
            ..|.||::.....|.::...:..|..:: ::| ..|||                   |....:|.
  Rat   417 LTRYNKELSMVKIPSKTSAKYLEKKFNKSEKYISENILVLDIFFEALNYETIEQKKAYEVAALLG 481

  Fly   385 NVGGVLGICIGCSFISGFEL---IYFLV 409
            ::||.:|:.||.|.::..||   ||.|:
  Rat   482 DIGGQMGLFIGASLLTILELFDYIYELI 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk27	NP_647826.2	ASC	15..407	CDD:459966	98/479 (20%)
Asic2	NP_037024.2	ENaC	64..557	CDD:273304	100/483 (21%)