Protein Alignment ppk27 and Scnn1a

DIOPT Version :10

• Sequence 1: NP_647826.2
• Gene: ppk27 / 38440
• FlyBaseID: FBgn0035458
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_113736.1
• Gene: Scnn1a / 25122
• RGDID: 3639
• Length: 699
• Species: Rattus norvegicus
• Alignment Length: 555
• Identity: 108/555 - (19%)
• Similarity: 193/555 - (34%)
• Gaps: 177/555 - (31%)

  Fly     8 FNKTVVEYFR----KTSLNGFGLLYFIRKRRIQRIFWFL--FISFGILFASYAVFSMVLEFLSYS 66
            |:::..|.|:    .|:::|...|...:..|::..||.:  ..:||:::..:|:  :..|:|||.
  Rat    77 FHRSYRELFQFFCNNTTIHGAIRLVCSKHNRMKTAFWAVLWLCTFGMMYWQFAL--LFEEYLSYP 139

  Fly    67 TIADLSELKVLEDEIHFPELKICS----------------------------GYKFSYRNMLA-- 101
            ...:::   :..|::.||.:.:|:                            .|..||.....
  Rat   140 VSLNIN---LNSDKLVFPAVTVCTLNPYRYTEIKEELEELDRITEQTLFDLYKYNSSYTRQAGAR 201

  Fly   102 --SAHDLVSSQNKSLDYWLNKLSLLSGYFDALSVK--AENVDDLNSLLDIK-------------- 148
              |:.||:.    :..:.|.:|......:...:.:  :.:|.|.|..:|.|
  Rat   202 RRSSRDLLG----AFPHPLQRLRTPPPPYSGRTARSGSSSVRDNNPQVDRKDWKIGFQLCNQNKS 262

  Fly   149 -----------------------NISSFLLALTPACE-----SLILKCKLNNIPANCLKLFTLKA 185
                                   ||.|.|...:||.|     :.|..|:.|..|.|.........
  Rat   263 DCFYQTYSSGVDAVREWYRFHYINILSRLSDTSPALEEEALGNFIFTCRFNQAPCNQANYSKFHH 327

  Fly   186 YNDGNCCVL---RNSNL--------TGELTLFMDSSQIDEYPLNGNLPGFSLHV-----PSW--Q 232
            ...|||...   .||||        ...|:|.:.:.|.|..||...:.|..:.|     |::  .
  Rat   328 PMYGNCYTFNDKNNSNLWMSSMPGVNNGLSLTLRTEQNDFIPLLSTVTGARVMVHGQDEPAFMDD 392

  Fly   233 GRVSINPGEMAAVEIEVMELQ------GNSQLNEYAVEKRACYFSQEGESREKCLHECRIKATLI 291
            |..::.||...::.:....|.      |:...|...|..:..|.|:  .:::.|:|.|..:..:.
  Rat   393 GGFNLRPGVETSISMRKEALDSLGGNYGDCTENGSDVPVKNLYPSK--YTQQVCIHSCFQENMIK 455

  Fly   292 NCQC--VPYP-------FEFRTQ-KFGYC--------TLENIRCLQLVERNWSPAQCPQCLPLCN 338
            .|.|  :.||       .::|.| .:|||        :|:::.|..            :|...|:
  Rat   456 KCGCAYIFYPKPKGVEFCDYRKQSSWGYCYYKLQGAFSLDSLGCFS------------KCRKPCS 508

  Fly   339 QLFYRL-----------------------NKQILGHLHPWRSELNFKFKTPHRQRYKTNI---LY 377
            .:.|:|                       |...:.:.....::||..||   ...||||.   ..
  Rat   509 VINYKLSAGYSRWPSVKSQDWIFEMLSLQNNYTINNKRNGVAKLNIFFK---ELNYKTNSESPSV 570

  Fly   378 HWYQMLSNVGGVLGICIGCSFISGFELIYFLVFRL 412
            ....:|||:|....:..|.|.:|..|:.. |:|.|
  Rat   571 TMVSLLSNLGSQWSLWFGSSVLSVVEMAE-LIFDL 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk27	NP_647826.2	ASC	15..407	CDD:459966	103/541 (19%)
Scnn1a	NP_113736.1	ENaC	80..677	CDD:273304	107/552 (19%)