Protein Alignment ppk27 and asic-2

DIOPT Version :10

• Sequence 1: NP_647826.2
• Gene: ppk27 / 38440
• FlyBaseID: FBgn0035458
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_492099.1
• Gene: asic-2 / 189058
• WormBaseID: WBGene00012137
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 484
• Identity: 100/484 - (20%)
• Similarity: 171/484 - (35%)
• Gaps: 156/484 - (32%)

  Fly    34 RIQRIFWFLFISFGILFASYAVFSMVLEFLSYSTIADLSELKVLEDEIHFPELKIC--SGYKFSY 96
            :|.||||.....|.:...:|.::.::.:|.||....:   .::|.::..||.:.:|  :.||:|
 Worm    31 KISRIFWIAIFLFVLGMFAYELYILIAKFFSYPATVN---TEILFEKQIFPVVTVCNMNPYKYS- 91

  Fly    97 RNMLASAHDLVSSQNKSLDYWLNKLSLLSGYFDAL---------SVKAENVD--DLNS------L 144
               :..::...||.|          :|::.|.||.         .:.|:|.:  ||:|      :
 Worm    92 ---VVKSNSAFSSVN----------TLMTTYSDATVGTFSTDKWGLYADNDETYDLDSRAADALV 143

  Fly   145 LDIKNISSFLLALTPAC---ESLILKCKLNNIPAN--------------CLKLFTLKAYNDG--- 189
            |:...||.  .|..||.   ..||..|....||.:              |.      ::|:.
 Worm   144 LEANLISD--TAKVPALYTYADLIQDCSFAGIPCSESDFTKFIDPVYGACY------SFNEDASL 200

  Fly   190 NCCVLRNSNLTGELTLFMDSSQIDEYPLNGNLPGFSLHVPSWQG-RVSINP-------------- 239
            |..|.|.....| |.|.:..:|.   ..|||..  ||......| |:.:|.
 Worm   201 NYSVSREGIQFG-LKLMLTVTQT---KTNGNTD--SLPTTKLAGARIGVNSRGSSPGLDSNGIDA 259

  Fly   240 --GEMAAVEIEVMELQGNSQLNEYAVEKRACYFSQEGESR----------EKCLHECRIKATLIN 292
              |..:||.:.:.:       |..|.:.......:|.:|.          |.|.:.|:.:.|:..
 Worm   260 GVGYESAVSVSLTQ-------NVRAKKPYGTCVDREPDSSDYYKDFIYTLETCFNGCKQRDTIAK 317

  Fly   293 CQCV-PYPFEFRTQKFGYCTLENIRCLQLVERNWSPA--------QCPQCLPLCNQLFYRLNKQI 348
            |||. |......|.........::.|||.::.|.:.:        :| .|.|.|::..|.....:
 Worm   318 CQCANPRLALGSTDTACQPIKADLDCLQTLKGNQTSSTPNIDLLVEC-NCNPPCDESTYTPTVSL 381

  Fly   349 -----------------LGHLHPWRSELNFKF--KTPHRQRYKTN----------ILYHWY---- 380
                             :|..    |..|.||  |:..::.|..|          :.|..|
 Worm   382 AQFPSTSYYVATSSTAGVGSC----SSTNSKFSSKSDCQKWYNNNGMIIQVFLETLSYELYTETA 442

  Fly   381 -----QMLSNVGGVLGICIGCSFISGFEL 404
                 .:::::||..|:.:|.|.||..|:
 Worm   443 GYTVSNVINDLGGQAGLWLGLSVISVVEM 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk27	NP_647826.2	ASC	15..407	CDD:459966	100/484 (21%)
asic-2	NP_492099.1	deg-1	12..474	CDD:273309	100/484 (21%)