Protein Alignment ppk27 and Asic3

DIOPT Version :10

• Sequence 1: NP_647826.2
• Gene: ppk27 / 38440
• FlyBaseID: FBgn0035458
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: XP_006535700.1
• Gene: Asic3 / 171209
• MGIID: 2159339
• Length: 563
• Species: Mus musculus
• Alignment Length: 546
• Identity: 89/546 - (16%)
• Similarity: 159/546 - (29%)
• Gaps: 228/546 - (41%)

  Fly    20 SLNGFGLLYFIRKRRIQRIFWFLFISFGILFASYAVFSMVLEFLSYSTIADLSELKVLEDEIHFP 84
            :::|.|.::......::|..|...:...:....|.|...|..:..:.....|.|.:  ..::.||
Mouse    26 TMHGLGHIFGPGGLTLRRGLWATAVLLSLAAFLYQVAERVRYYGEFHHKTTLDERE--SHQLTFP 88

  Fly    85 ELKICSGYKFSYRNMLASAHDLVSSQNKSLDYWLNKLSLLSGYFDALSVKAENVDDLNSLLDIKN 149
            .:.:|:....  |....:.:||         :|..  :.|.|                  ||...
Mouse    89 AVTLCNINPL--RRSRLTPNDL---------HWAG--TALLG------------------LDPAE 122

  Fly   150 ISSFLLAL--TPA----------------------CESLILKCKLNNIPA---NCLKLFTLKAYN 187
            .:::|.||  .||                      .|.::|.|:....|.   |...:||    .
Mouse   123 HAAYLRALGQPPAPPGFMPSPTFDMAQLYARAGHSLEDMLLDCRYRGQPCGPENFTVIFT----R 183

  Fly   188 DGNCCVLRNSNLTGE-------------LTLFMDSSQIDEYPLNGNLPGFSLHVPSWQGRVSINP 239
            .|.|... ||...|.             |.:.:|..| :||            :|.|:
Mouse   184 MGQCYTF-NSGAQGAELLTTPKGGAGNGLEIMLDVQQ-EEY------------LPIWK------- 227

  Fly   240 GEMAAVEIEV-MELQGNSQLNEYAVEKRACYFSQEGESREKCLHECRIKATLINCQCVPYPFEFR 303
             :|.....|| :.:|.:.|....|:::.. :.:..|       |:     |.::||  .....|.
Mouse   228 -DMEETPFEVGIRVQIHGQEEPPAIDQLG-FGAAPG-------HQ-----TFVSCQ--QQQLSFL 276

  Fly   304 TQKFGYCTLEN------------------------IRCLQLVERNWSPAQC-------PQCLPLC 337
            ...:|.|...:                        |.|....|..:...:|       |...|:|
Mouse   277 PPPWGDCNTASVDPDFDPEPSDPLGSPSSSPPYSLIGCRLACESRYVARKCGCRMMHMPGNSPVC 341

  Fly   338 NQLFYR-LNKQILGHLH------PWRSELNFK--------------------------------- 362
            :...|: .....||..|      |..|:::..
Mouse   342 SPQQYKDCASPALGKAHLFSLPVPIHSDIDHNPLGQVLLFLALRPADAMLRKDTCVCPNPCATTR 406

  Fly   363 -------FKTPHR-------------QRYKT-NIL-------------------YHWYQMLSNVG 387
                   .:.|.|             :.|.| |:|                   |...::|.::|
Mouse   407 YAKELSMVRIPSRASARYLARKYNRSETYITENVLVLDIFFEALNYEAVEQKAAYEVSELLGDIG 471

  Fly   388 GVLGICIGCSFISGFELIYFL--VFR 411
            |.:|:.||.|.::..|::.:|  ||:
Mouse   472 GQMGLFIGASLLTILEILDYLCEVFQ 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk27	NP_647826.2	ASC	15..407	CDD:459966	86/538 (16%)
Asic3	XP_006535700.1	ENaC	21..546	CDD:273304	89/546 (16%)