Protein Alignment ppk27 and Asic2

DIOPT Version :10

• Sequence 1: NP_647826.2
• Gene: ppk27 / 38440
• FlyBaseID: FBgn0035458
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: XP_006532059.1
• Gene: Asic2 / 11418
• MGIID: 1100867
• Length: 596
• Species: Mus musculus
• Alignment Length: 516
• Identity: 97/516 - (18%)
• Similarity: 168/516 - (32%)
• Gaps: 200/516 - (38%)

  Fly    36 QRIFWFLFI--SFGILFASYAVFSMVLEFLSYSTIADLSELKVLED---EIHFPELKICSG---- 91
            :|..|.|..  |.|:|.:..:  :.:|.:||:.     |..:|..:   ::.||.:.:|:.
Mouse    85 RRALWVLAFCTSLGLLLSWSS--NRLLYWLSFP-----SHTRVHREWSRQLPFPAVTVCNNNPLR 142

  Fly    92 ----------YKFSYRNML---ASAHDLVSS---QNKSLDYWLNKLS-----LLSGYFDALSVKA 135
                      |...:..:|   .:|..|||.   .::....|..||:     |...:|:.:|
Mouse   143 FPRLSKGDLYYAGHWLGLLLPNRTARPLVSELLRGDEPRRQWFRKLADFRLFLPPRHFEGIS--- 204

  Fly   136 ENVDDLNSLLDIKNISSFLLALTPACESLILKCKL--------NNIPANCL-------------- 178
                           ::|:..|....|.::|.||.        |....:|.
Mouse   205 ---------------AAFMDRLGHQLEDMLLSCKYRGELCGPHNFSSVSCPPREPALSDPALPRS 254

  Fly   179 ---------------------KLFTLKAYNDGNCCVLRNSNLTGE-LTLFMDSSQIDEY-PLNGN 220
                                 |.:...:..||...:......||. |.:.:|..| ||| |:.|.
Mouse   255 PEALRWAPGTGHQAPVFTKYGKCYMFNSGEDGKPLLTTVKGGTGNGLEIMLDIQQ-DEYLPIWGE 318

  Fly   221 ------------------------------LPGFSLHVPSWQGRVSINP---GEMAAVEIEVMEL 252
                                          .|||...|.:.:.|::..|   ||..:.|:
Mouse   319 TEETTFEAGVKVQIHSQSEPPFIQELGFGVAPGFQTFVATQEQRLTYLPPPWGECRSSEM----- 378

  Fly   253 QGNSQLNEYAVEKRACYFSQEGESREKCLHECRIKATLINCQC--VPYPFEFRTQKFGYCTLENI 315
             |......|::              ..|..:|..:..:.||.|  |..|.:     ..:||.|..
Mouse   379 -GLDFFPVYSI--------------TACRIDCETRYIVENCNCRMVHMPGD-----APFCTPEQH 423

  Fly   316 R-CLQ-----LVER--NWSPAQCPQCLPLCNQLFYRLNKQILGHLHPWRSELNFKFKTPHR-QRY 371
            : |.:     |.|:  |:...:.|     ||  ..|.||::.....|.::...:..|..:: ::|
Mouse   424 KECAEPALGLLAEKDSNYCLCRTP-----CN--LTRYNKELSMVKIPSKTSAKYLEKKFNKSEKY 481

  Fly   372 -KTNIL-------------------YHWYQMLSNVGGVLGICIGCSFISGFEL---IYFLV 409
             ..|||                   |....:|.::||.:|:.||.|.::..||   ||.|:
Mouse   482 ISENILVLDIFFEALNYETIEQKKAYEVAALLGDIGGQMGLFIGASILTILELFDYIYELI 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk27	NP_647826.2	ASC	15..407	CDD:459966	95/512 (19%)
Asic2	XP_006532059.1	ENaC	64..590	CDD:273304	97/516 (19%)