Protein Alignment ppk27 and asic5

DIOPT Version :10

• Sequence 1: NP_647826.2
• Gene: ppk27 / 38440
• FlyBaseID: FBgn0035458
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: XP_017951381.2
• Gene: asic5 / 100498195
• XenbaseID: XB-GENE-983430
• Length: 852
• Species: Xenopus tropicalis
• Alignment Length: 517
• Identity: 98/517 - (18%)
• Similarity: 176/517 - (34%)
• Gaps: 152/517 - (29%)

  Fly     1 MSRIVTAFNKTVVEYFRKTSL----------NGF-------GLLYFI------RKRRIQRIFWFL 42
            |...:..:...|:.|.||.|:          :||       |:...:      :..:.:...|..
 Frog   354 MGENICGYWSKVLLYLRKHSVPSLEERKKYNHGFATSTSFHGVHNLVENGGSGKNSKFRTAIWTS 418

  Fly    43 FISFGILFASYAVFSMVLEFLSYSTIADLSELKVLEDEIHFPELKICSGYKFSYRNMLASAHDLV 107
            .:|..|:.|.:.|.:.|:.:.|:.|...::...|  :.|.||.:..|:..:|..:
 Frog   419 VVSVFIIMACWQVCTRVINYFSWPTTTSVNVQYV--ENIDFPAITFCNLNRFQTK---------- 471

  Fly   108 SSQNKSLDYWLNKLSLLSGYFDALSVKAENVDDLNSLLDI-KNIS--------SFLLALTPACES 163
            :..|.|:.::|..:.....:|.:::.....:.::...|.: ||.|        .|.|.     .|
 Frog   472 AVNNLSIAFFLWNIVSAVLHFTSIASDPGEMQEVTDFLKLNKNFSIKEFTKNYGFYLN-----NS 531

  Fly   164 LILKCKLNNIPANCL-----KLFTLKAYNDGNC------CVLRNSNLT----GELTLF-MDSSQI 212
            .:|||.....|  |.     .:||    ..|||      .|..|..:|    |...|| :..::.
 Frog   532 TLLKCSFFGYP--CYPEDFEHIFT----EYGNCYTFNYNTVSMNKRITTAGRGLSVLFDIKQTEF 590

  Fly   213 DEYPLNG-----------------NLPGFSLHVPS-WQGRVSINPGEMAAVEIEVMELQGNSQLN 259
            .:.|..|                 ...|..||.|: ....||:...:....|....|...:.:|.
 Frog   591 TDEPSLGFVDAGISFVLHSPLVPPRFDGLGLHSPAGMHAHVSMRRFKTVIQEHPWGECNPSLKLK 655

  Fly   260 EYAVEKRACYFSQEGESREKCLHECRIKATLINCQCVPYPFEFRTQKFGYCTLENI-----RCLQ 319
            .:.:      :|..|     ||.||:.......|.|:|:......::   |.|:.:     |.|.
 Frog   656 YHEI------YSTYG-----CLQECKSYYIQNECGCIPFLLPGNGKE---CDLQQLYNCVSRALY 706

  Fly   320 LVER----------NWSPAQCPQ---------------------CLPLCNQLFYRLNKQILGHLH 353
            .:|:          :..|..|.:                     ...|.....|..|.  |.::.
 Frog   707 TIEKSELCSMGTYNSTCPVPCEETDFPATISYSTFPSDKAAQFLSAKLSKSALYMRNN--LVYID 769

  Fly   354 PWRSELNFKFKTPHRQRYKTNILYHWYQMLSNVGGVLGICIGCSFISGFELIYFLVFRLWTN 415
            ....|:|:|.....:....:       ::|||:||.||:..|.|.|:..|::.:    |:||
 Frog   770 IKYHEMNYKIMKQQKALTAS-------ELLSNIGGQLGLFCGASMITIIEVLEY----LFTN 820

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk27	NP_647826.2	ASC	15..407	CDD:459966	93/493 (19%)
asic5	XP_017951381.2	Inhibitor_I29	66..129	CDD:462410
		Peptidase_C1A	158..360	CDD:239068	1/5 (20%)
		ASC	387..816	CDD:459966	88/474 (19%)