Protein Alignment ppk27 and asic4

DIOPT Version :10

• Sequence 1: NP_647826.2
• Gene: ppk27 / 38440
• FlyBaseID: FBgn0035458
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: XP_031749131.1
• Gene: asic4 / 100486325
• XenbaseID: XB-GENE-940165
• Length: 535
• Species: Xenopus tropicalis
• Alignment Length: 478
• Identity: 89/478 - (18%)
• Similarity: 166/478 - (34%)
• Gaps: 124/478 - (25%)

  Fly     5 VTAFNKTVVEYFRKTSLNGFGLLYFIRKRRIQRIFWFLFISFGILFASYAVFSMVLEFLSYSTIA 69
            |.|..:.:..:...::|:|...::...:..|::..|.|.....:||..|.|....|.:|.:..:.
 Frog    34 VPAAGRDLAAFASTSTLHGLRHIFQTGRLGIKQSLWALAFLASLLFFLYQVAKCALYYLEHPHVT 98

  Fly    70 DLSELKVLEDEIHFPELKICSGYKFSYRNMLASAHDLVSSQNKSLDYWLNKLSLL-----SGYFD 129
            .:.| :|: .|:.||.:.||:..:|  |:...:..|:         |.|..|:.|     .|:.|
 Frog    99 AVDE-EVM-GEMIFPAITICNINRF--RHSALTDPDI---------YHLANLTGLPPKDREGHRD 150

  Fly   130 ALSVKAENVDDLNSLLDIKNISSFLLA-LTPACESLILKCKLNNIPANCLKLFTLKAYNDGNCC- 192
                 ::.:.|...:|||.|.:...|| :..:|......|...|        |::.....|.|.
 Frog   151 -----SDLMYDDPDMLDIVNRTGHQLAEMLKSCNFSGDSCSAQN--------FSVVFTRYGKCYT 202

  Fly   193 ---------VLRNSNLTGELTLFMDSSQIDEYPL------------------------------N 218
                     |.|...:...|.:.:|..|.:..|:                              .
 Frog   203 FNADKKHPKVSRQGGMGNGLEIMLDIQQEEYLPIWRETNETSFEAGIRVQIHSQDEPPYIHQMGF 267

  Fly   219 GNLPGFSLHVPSWQGRV-----------SINPGE-----MAAVEIEVMELQGNSQLNEYAVEKRA 267
            |..|||...|...:.|:           |..|||     .:...|....||..   .|..:.|.|
 Frog   268 GVSPGFQTFVSCQEQRMTYLPQPWGNCRSSIPGEEFLSGYSTYSISACRLQCE---KEAVIRKCA 329

  Fly   268 CYFSQEGESREKC---LHEC-------RIKATLINCQCVPYPFEFR--TQKFGYCTLENIRCLQL 320
            |.......:...|   ::.|       .::.|...|.| |.|....  :::.....:.|....:.
 Frog   330 CRMVHMPGNETICSPVMYMCADHILDNMVEDTSEKCSC-PTPCNLTRYSKEISMVRIPNKGSARY 393

  Fly   321 VERNWSPAQCPQCLPLCNQLFYRLNKQILGHLHPWRSELNFKFKTPHRQRYKTNILYHWYQMLSN 385
            :.|.::.          |:.:.|.|..:          |:..|:..:.:..:....|....:|.:
 Frog   394 LARKYNK----------NETYIRENFLV----------LDIFFEALNYETIEQKKAYDLPSLLGD 438

  Fly   386 VGGVLGICIGCSFISGFELIYFL 408
            :||.:|:.||.||::..|::.::
 Frog   439 IGGQMGLFIGASFLTILEILDYM 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk27	NP_647826.2	ASC	15..407	CDD:459966	87/465 (19%)
asic4	XP_031749131.1	ENaC	39..514	CDD:273304	87/473 (18%)