DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32264 and Phactr3

DIOPT Version :9

Sequence 1:	NP_728897.1	Gene:	CG32264 / 38438	FlyBaseID:	FBgn0052264	Length:	1008	Species:	Drosophila melanogaster
Sequence 2:	XP_038961478.1	Gene:	Phactr3 / 362284	RGDID:	1303029	Length:	558	Species:	Rattus norvegicus

Alignment Length:	761	Identity:	207/761 - (27%)
Similarity:	294/761 - (38%)	Gaps:	282/761 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   279 RTNSLGSGTRTPPLERKSKLSALGRFFKPWKWRRKKKSEKFEAASKSLERKISVRANRDELVQKG 343
            |:..|.||.||||:.|.|||:.|||.|||||| ||||:||.:..:.:||:|::.|..|:||:::|
  Rat    49 RSEPLVSGIRTPPVRRNSKLATLGRIFKPWKW-RKKKNEKLKQTTSALEKKMAGRQGREELIKQG 112

  Fly   344 IL--MPESPLGNIPEPGEESYYNNSNSGATANGSLLNSAVHNNSMSQANNSINATTGNPLISAAQ 406
            :|  |.:........|.|.|....|...|....:|.:..|.              .|:|..|...
  Rat   113 LLEMMEQDSESKACSPKEGSQPAQSEPSAGEQETLTSEGVQ--------------PGSPSASGTD 163

  Fly   407 QQLNQGLPNSISVQQFNGQNQNPQNSMANGLVGGGGGGGDGSSDTSSLSGGVPHSQSAPQQLGVG 471
            |.....|.:|         :.:|                |.::..||.|.|
  Rat   164 QASQDELLSS---------DAHP----------------DDTAKMSSASSG-------------- 189

  Fly   472 QPPPPLTPLAQHHQALAQQLQQRFAISNNNEPRKDKTDAQQQQHGGNGTISTPNIEQPTCQGSML 536
                                              ::.||      ||...:|....|....||:.
  Rat   190 ----------------------------------EEADA------GNLLPTTDEPSQEALSGSLD 214

  Fly   537 PPPGGGGHHQVDGSGKMERPNTLAGANKLTRRGVNICYHNEHMYGEDGKMVGGPPGSTPPPYPGG 601
            .||           ..:||
  Rat   215 SPP-----------RTLER---------------------------------------------- 222

  Fly   602 KLPPGVMLSELPEPPIPLSEIGPIP-PPPMFSTPSPTLIAGRP---HGPGAVNDQDYQQDYDYDD 662
                  ..|:||.||:       :| |||..|:.:...:.|:.   .|....|
  Rat   223 ------SASQLPSPPL-------LPTPPPKASSKATKNVTGQAALFQGSSMKN------------ 262

  Fly   663 NDPDQDELDSDDEYAPYGGNHVRMMDTQRVEEIPAKEPKPNAVPLKSALKKKGGMQPASASTPVT 727
            |:|                            .:..:.|.|...|..:.:.:           |:.
  Rat   263 NEP----------------------------VLRGQLPTPTGSPHLTTVHR-----------PLP 288

  Fly   728 PTQEHGAGSAATAAAMANSNGGIGSMAAAAAAAAQQSANQRPLVVRQDAAGNNYSLKPILRPRIR 792
            |::.                  |..:..|.|...:|.:.|          |......|..|..:|
  Rat   289 PSRV------------------IEELHRALATKHRQDSFQ----------GRECRGSPKKRMDVR 325

  Fly   793 LCRQQMFN-------------------IQLPCTVENKENARPFVIRESSSDSDDSDGHIVYRDED 838
            |.|.....                   .....:.|||||     :..||...||.   ::|:||:
  Rat   326 LSRTSSMERGKERDEAWSFDGASENKWTAAKDSEENKEN-----LILSSELKDDL---LLYQDEE 382

  Fly   839 --NDNT---RLAKLARKESLSLKLQLRPDKQDLINRNILHQVNDNELKESKEAIGARLIRRLSMR 898
              ||:.   .|.:..:||.|::||:.||.||:|.:|||..:..|.|.:|.::.|..:|.:|||.|
  Rat   383 ALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQR 447

  Fly   899 PTAEELVERNILKTQSPAEEKKQKEEKKSYLLRKLSFRPTVEELKEKKI-IRFNDYIEVTQAHDY 962
            |..|||..|||||.::...|::::.|.|..|.|||:.||||:||:::|| |||:||:||.:|.||
  Rat   448 PAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVARAQDY 512

  Fly   963 DRRADKPWTRLTPKDKAAIRKELNEFKSSEMAVHEGSRHLTRFHRP 1008
            |||||||||||:..|||||||||||:||:||.||..|:||||||||
  Rat   513 DRRADKPWTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32264	NP_728897.1	RPEL	325..347	CDD:280851	9/23 (39%)
		RPEL	851..876	CDD:128947	12/24 (50%)
		RPEL	889..914	CDD:128947	14/24 (58%)
		RPEL	927..952	CDD:128947	15/25 (60%)
Phactr3	XP_038961478.1	DUF5401	<393..546	CDD:375164	83/152 (55%)
Phactr3	XP_038961478.1	RPEL	439..463	CDD:128947	14/23 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340358
Domainoid	1	1.000	103	1.000	Domainoid score	I6615
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	309	1.000	Inparanoid score	I2529
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44867
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12751
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.990