DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32264 and F26H9.2

DIOPT Version :9

Sequence 1:	NP_728897.1	Gene:	CG32264 / 38438	FlyBaseID:	FBgn0052264	Length:	1008	Species:	Drosophila melanogaster
Sequence 2:	NP_492478.2	Gene:	F26H9.2 / 172753	WormBaseID:	WBGene00009174	Length:	508	Species:	Caenorhabditis elegans

Alignment Length:	754	Identity:	195/754 - (25%)
Similarity:	283/754 - (37%)	Gaps:	291/754 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   277 AIRTNSLGSGTRTPPLERKSKLSALGRFF----KPWKWRRKKKSEKFEAASKSLERKISVRANRD 337
            |..:.|.||.::|....|||...|..:|:    :|||||             :|.||  ||.:..
Worm    23 ATSSTSGGSKSKTGRSPRKSISFASSKFWLRLVRPWKWR-------------NLRRK--VRRSDS 72

  Fly   338 ELVQKGILMPESPLGNIPEPGEESYYNNSNSGATANGSLLNSAVHNNSMSQANNSINATTGNPLI 402
            |                                           .::|.::||:..|....:|
Worm    73 E-------------------------------------------RSSSQNRANSVSNFPRTSP-- 92

  Fly   403 SAAQQQLNQGLPNSISVQQFNGQNQNPQNSMANGLVGGGGGGGDGSSDTSSLSGGVPHSQSAPQQ 467
                     .||...|:.:.:.....                ..||:|.|......|.:.||
Worm    93 ---------SLPELSSIVREDSAEMK----------------ASGSNDNSEAITYRPATSSA--- 129

  Fly   468 LGVGQPPPPLTPLAQHHQALAQQLQQRFAISNNNEPRK---DKTDAQQQQHGGNGTISTPNIEQP 529
                         :.:|             :.|:||:.   |.|..         :|....|:.|
Worm   130 -------------STNH-------------AENSEPQPLIVDPTHI---------SIVRTKIQDP 159

  Fly   530 TCQGSMLPPPGGGGHHQVDGSGKMERPNTLAGANKLTRRGVNICYHNEHMYGEDGKMVGGPPGST 594
            :      |.|.|       .|.:::|...:...:..          |..::            :.
Worm   160 S------PDPSG-------ASSEIQRVQFIQSTSTA----------NPAIF------------TA 189

  Fly   595 PPPYPGGKLPPGVMLSELPEPPIPLSEIGPIPPPPMFSTPSPTLIAGRPHGPGAVNDQDY-QQDY 658
            |||      ||.:::.               ||||                    .|:|. :::.
Worm   190 PPP------PPSLVIQ---------------PPPP--------------------GDRDSDEENI 213

  Fly   659 DYDDNDPDQDELD---SDDEYAPYGGNHVRMMDTQRVEEIPAKEPKPNAVPLKSALKKKGGMQPA 720
            :||.:...:.|.|   |.|..........||: .:....|.||||...|.|.|..|::.|  ||:
Worm   214 NYDQSTESEGEEDMNRSADRRGELSPQTSRML-KEGYRRIEAKEPNFTAQPDKPNLRRPG--QPS 275

  Fly   721 ----SASTPVTPTQEHGAGSAATAAAMANSNGGI---GSMAAAAAAAAQQSANQRPLVVRQDAAG 778
                :..|..:..::....|..|..  ::|:..|   ....:.|||||:::||..|
Worm   276 RLRLNGKTGKSSKEDTELPSKLTDD--SDSDAPIQYRDDPISVAAAAARRAANVAP--------- 329

  Fly   779 NNYSLKPILRPRIRLCRQQMFNIQLPCTVENKENARPFVIRESSSDSDDSDGHIVYRDEDND--- 840
                                                    ..||:|.||        ||:.|
Worm   330 ----------------------------------------PGSSTDEDD--------DEEEDVPI 346

  Fly   841 --NTRLAKLARKESLSLKLQLRPDKQDLINRNILHQVNDNELKESKEAIGARLIRRLSMRPTAEE 903
              |...:|:||:::::|||...|.|.|     |..|..|:..|..|.| ..:|.|:||.|||.||
Worm   347 PRNGLASKVARRDTMALKLDAPPCKND-----INGQTADDRKKLMKTA-SIKLARKLSERPTPEE 405

  Fly   904 LVERNILKTQSPAEEKKQKEEKKSYLLRKLSFRPTVEELKEKKIIRFNDYIEVTQAHDYDRRADK 968
            |.:||||:.:.....:.. |||:..||||||||||::||||::||:|.||:|||||..|||:.||
Worm   406 LEDRNILRRRGMTSSEAM-EEKRKLLLRKLSFRPTIKELKEQQIIQFADYVEVTQAEVYDRKTDK 469

  Fly   969 PWTRLTPKDKAAIRKELNEFKSSEMAVHEGSRHLTRFHR 1007
            |||||||.|||.||||||:||::||.|||.||..|||||
Worm   470 PWTRLTPSDKAMIRKELNDFKATEMDVHEESRVFTRFHR 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32264	NP_728897.1	RPEL	325..347	CDD:280851	6/21 (29%)
		RPEL	851..876	CDD:128947	8/24 (33%)
		RPEL	889..914	CDD:128947	14/24 (58%)
		RPEL	927..952	CDD:128947	17/24 (71%)
F26H9.2	NP_492478.2	RPEL	392..415	CDD:128947	14/22 (64%)
F26H9.2	NP_492478.2	RPEL	428..453	CDD:128947	17/24 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159338
Domainoid	1	1.000	91	1.000	Domainoid score	I4857
eggNOG	1	0.900	-	-		E1_KOG4339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto19313
orthoMCL	1	0.900	-	-		OOG6_108169
Panther	1	1.100	-	-	LDO	PTHR12751
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3634
SonicParanoid	1	1.000	-	-		X711
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.730