DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10862 and UBE2R2

DIOPT Version :9

Sequence 1:	NP_647823.1	Gene:	CG10862 / 38437	FlyBaseID:	FBgn0035455	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_060281.2	Gene:	UBE2R2 / 54926	HGNCID:	19907	Length:	238	Species:	Homo sapiens

Alignment Length:	156	Identity:	52/156 - (33%)
Similarity:	82/156 - (52%)	Gaps:	19/156 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 LRREISEFSTDQTEGCKAEMVGD-NLFHWVATIPGPSETVYEGGRFRVEIVFPRNYPFYPPYLAF 276
            |..|:.....:..||.:..:|.: :|::|...|.||..|:||||.|:..|.||.:||:.||...|
Human    13 LMLELKSLQEEPVEGFRITLVDESDLYNWEVAIFGPPNTLYEGGYFKAHIKFPIDYPYSPPTFRF 77

  Fly   277 LTKTYHCNIALSGRICLDIL-------------GSKWSPALSVSKVLISIMSLLADPNPHDPMEV 328
            |||.:|.||..:|.:|:.||             ..:|:|..:|..:|:|::|||.:||...|..|
Human    78 LTKMWHPNIYENGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANV 142

  Fly   329 SVADVFKGNRALHDKNAREWTKKYAK 354
            ..:.:|   |...|...::  |:||:
Human   143 DASVMF---RKWRDSKGKD--KEYAE 163

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10862	NP_647823.1	COG5078	207..354	CDD:227410	51/154 (33%)
CG10862	NP_647823.1	UQ_con	212..349	CDD:278603	49/149 (33%)
UBE2R2	NP_060281.2	UBCc	11..169	CDD:238117	52/156 (33%)
UBE2R2	NP_060281.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	194..238
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910