DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10862 and UBE2C

DIOPT Version :9

Sequence 1:	NP_647823.1	Gene:	CG10862 / 38437	FlyBaseID:	FBgn0035455	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_008950.1	Gene:	UBE2C / 11065	HGNCID:	15937	Length:	179	Species:	Homo sapiens

Alignment Length:	141	Identity:	56/141 - (39%)
Similarity:	75/141 - (53%)	Gaps:	9/141 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   212 RLRREISEFSTDQTEGCKAEMVGDNLFHWVATIPGPSETVYEGGRFRVEIVFPRNYPFYPPYLAF 276
            ||::|:........:|..|....||||.||.||.|.:.||||..|:::.:.||..||:..|.:.|
Human    34 RLQQELMTLMMSGDKGISAFPESDNLFKWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKF 98

  Fly   277 LTKTYHCNIALSGRICLDILGSKWSPALSVSKVLISIMSLLADPNPHDPMEVSVADVFKGNRALH 341
            ||..||.|:...|.||||||..|||....|..:|:||.|||.:||...|:....|:::|...|.
Human    99 LTPCYHPNVDTQGNICLDILKEKWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWKNPTAF- 162

  Fly   342 DKNAREWTKKY 352
                    |||
Human   163 --------KKY 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10862	NP_647823.1	COG5078	207..354	CDD:227410	56/141 (40%)
CG10862	NP_647823.1	UQ_con	212..349	CDD:278603	53/136 (39%)
UBE2C	NP_008950.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31
UBE2C	NP_008950.1	UQ_con	34..170	CDD:395127	56/141 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910