Protein Alignment dar1 and SP6

DIOPT Version :10

• Sequence 1: NP_001097493.1
• Gene: dar1 / 38436
• FlyBaseID: FBgn0263239
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_954871.1
• Gene: SP6 / 80320
• HGNCID: 14530
• Length: 376
• Species: Homo sapiens
• Alignment Length: 426
• Identity: 112/426 - (26%)
• Similarity: 148/426 - (34%)
• Gaps: 129/426 - (30%)

  Fly   349 QHLYQHHPSLALPGLPPAVDVVELQLQQQHQQQQHLQHNNSSSSSPKLATPGDNSGNTSSYQQQY 413
            ||....|.|      ||.:|:..||..|.|             :||:   .||           |
Human    12 QHTEAPHAS------PPRLDLQPLQTYQGH-------------TSPE---AGD-----------Y 43

  Fly   414 ASQLVSGSGGGYLNGSSSNSYGYSWHSSQSFHTKYQIHPPSAAASATAS--ATATPTAQLGAQQQ 476
            .|.|..|.       ..|...|.....||.:..      |.|::..|..  .:.:|.|.....:.
Human    44 PSPLQPGE-------LQSLPLGPEVDFSQGYEL------PGASSRVTCEDLESDSPLAPGPFSKL 95

  Fly   477 QQQQQQQQLQQLCPPAAPST---------PSTSSSSISSSSASSASRHMFVPPLTPPSSDPGSPG 532
            .|.......:....|..|..         |.||              .|.:|......:.||.||
Human    96 LQPDMSHHYESWFRPTHPGAEDGSWWDLHPGTS--------------WMDLPHTQGALTSPGHPG 146

  Fly   533 SSMVAAAAAAAAQRRTTPPPPYQQGHVM-------GLINPPPTLQLLGGAATGSNNSCTTTLTTL 590
             ::.|.........:...|||:...|.:       .|:.||...:.|..||
Human   147 -ALQAGLGGYVGDHQLCAPPPHPHAHHLLPAAGGQHLLGPPDGAKALEVAA-------------- 196

  Fly   591 TPASAIQQQQQQPQQQQV---------PQQQPPPTPRSSGGGRRGRHSHHQPGTAAHIASLMSVR 646
                        |:.|.:         |:......|||||            .|.....:.:...
Human   197 ------------PESQGLDSSLDGAARPKGSRRSVPRSSG------------QTVCRCPNCLEAE 237

  Fly   647 TVRYNRRNNPE-LEKRRIHHCDFVGCSKVYTKSSHLKAHQRIHTGEKPYTCQWPECEWRFARSDE 710
              |......|: .:|:.:|:|...||.|.|.|:||||||.|.|:|::|:.|.|..|..||.||||
Human   238 --RLGAPCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDE 300

  Fly   711 LTRHYRKHTGAKPFKCIVCERSFARSDHLALHMKRH 746
            |.||.:.|||.|.|.|.||.|.|.||||||.|||.|
Human   301 LQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTH 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dar1	NP_001097493.1	COG5048	641..>724	CDD:227381	36/83 (43%)
		C2H2 Zn finger	671..688	CDD:275368	11/16 (69%)
		C2H2 Zn finger	696..718	CDD:275368	12/21 (57%)
		zf-H2C2_2	710..735	CDD:463886	14/24 (58%)
		C2H2 Zn finger	726..746	CDD:275368	14/19 (74%)
SP6	NP_954871.1	SP6_N	1..255	CDD:411693	63/343 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..70		23/103 (22%)
		9aaTAD. /evidence=ECO:0000269|PubMed:31375868	118..126		0/7 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	167..223		12/81 (15%)
		C2H2 Zn finger	259..278	CDD:275368	12/18 (67%)
		COG5048	<261..>336	CDD:227381	45/74 (61%)
		C2H2 Zn finger	286..308	CDD:275368	12/21 (57%)
		C2H2 Zn finger	316..336	CDD:275368	14/19 (74%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	333..376		3/4 (75%)